DDX28 - DEAD-box helicase 28 Gene

中文名称：死盒解旋酶 28

种属: Homo sapiens

同用名: MDDX28

关于 DDX28

功能概要

以保守基序 Asp-Glu-Ala-Asp (DEAD) 为特征的 DEAD 盒蛋白是推定的 RNA 解旋酶。它们涉及许多涉及 RNA 二级结构改变的细胞过程，例如翻译起始、核和线粒体剪接以及核糖体和剪接体组装。根据它们的分布模式，DEAD box 蛋白家族的一些成员被认为参与胚胎发生、精子发生以及细胞生长和分裂。这个基因是无内含子的。它编码 RNA 依赖性 ATP 酶。编码的蛋白质定位于线粒体和细胞核，可以在线粒体和细胞核之间运输。[RefSeq 提供，2008 年 7 月]

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is intronless. It encodes an RNA-dependent ATPase. The encoded protein is localized in the mitochondria and the nucleus, and can be transported between the mitochondria and the nucleus. [provided by RefSeq, Jul 2008]