1. Gene
  2. APOBR - apolipoprotein B receptor Gene

APOBR - apolipoprotein B receptor Gene

中文名称:载脂蛋白 B 受体

种属: Homo sapiens

同用名: APOB48R; APOB100R

基因 ID: 55911 | 基因类型: protein coding

关于 APOBR

Cytogenetic location: 16p12.1 Genomic coordinates (GRCh38): 16:28,494,643-28,498,964 (from NCBI)

This gene has 1 transcript (splice variant) and 82 orthologues. Biased expression in colon (RPKM 19.1), spleen (RPKM 14.5) and 12 other tissues.

功能概要

载脂蛋白 B48 受体是一种巨噬细胞受体,可与富含膳食甘油三酯 (TG) 的脂蛋白的载脂蛋白 B48 结合。该受体可为网状内皮细胞提供必需的脂质、脂溶性维生素和其他营养物质。如果被升高的血浆甘油三酯淹没,载脂蛋白 B48 受体可能会导致泡沫细胞形成、内皮功能障碍和动脉粥样硬化血栓形成。[RefSeq 提供,2008 年 7 月]

Apolipoprotein B48 receptor is a macrophage receptor that binds to the Apolipoprotein B48 of dietary triglyceride (TG)-rich lipoproteins. This receptor may provide essential lipids, lipid-soluble Vitamins and Other nutrients to reticuloendothelial cells. If overwhelmed with elevated plasma triglyceride, the Apolipoprotein B48 receptor may contribute to foam cell formation, endothelial dysfunction, and atherothrombogenesis. [provided by RefSeq, Jul 2008]

APOBR 基因产物(1)

mRNA Protein Name
NM_018690.4 NP_061160.3 apolipoprotein B receptor
蛋白主名 其他名称

apolipoprotein B receptor

apoB-48R

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus APOBR RGD RGD:1565169
Canis familiaris APOBR VGNC VGNC:37998
Macaca mulatta APOBR VGNC VGNC:69892
Mus musculus APOBR MGD MGI:2176230
Bos taurus APOBR VGNC VGNC:26030