2. Gene
  3. Mpc1 - mitochondrial pyruvate carrier 1 Gene

Mpc1 - mitochondrial pyruvate carrier 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Brp44l; 0610006G08Rik; 3830411I18Rik

基因 ID: 55951 | 基因类型: protein coding

关于 Mpc1

功能概要

Contributes to pyruvate transmembrane transporter activity. Acts upstream of or within cellular response to leukemia inhibitory factor; mitochondrial acetyl-CoA biosynthetic process from pyruvate; and mitochondrial pyruvate transmembrane transport. Located in mitochondrial inner membrane. Is expressed in several structures, including adrenal gland; hemolymphoid system; nervous system; olfactory epithelium; and retina. Human ortholog(s) of this gene implicated in mitochondrial pyruvate carrier deficiency. Orthologous to human MPC1 (mitochondrial pyruvate carrier 1). [provided by Alliance of Genome Resources, Apr 2022]

Mpc1 基因产物(3)

mRNA Protein Name
NM_001364918.1 NP_001351847.1 mitochondrial pyruvate carrier 1 isoform 2
NM_001364919.1 NP_001351848.1 mitochondrial pyruvate carrier 1 isoform 3
NM_018819.5 NP_061289.1 mitochondrial pyruvate carrier 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables pyruvate transmembrane transporter activity IDA
IDA: 通过直接分析推断
22628554 MGI
contributes to pyruvate transmembrane transporter activity IGI
IGI: 通过遗传相互作用推断
22628554 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within acetyl-CoA biosynthetic process from pyruvate IMP
IMP: 通过突变表型推断
22628558 MGI
involved in acetyl-CoA biosynthetic process from pyruvate IMP
IMP: 通过突变表型推断
22628558 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
acts upstream of or within mitochondrial pyruvate transmembrane transport IGI
IGI: 通过遗传相互作用推断
22628554 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
22628554 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mitochondrial pyruvate carrier 1

apoptosis-regulating basic protein

brain protein 44-like protein

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-138559 GW604714X Inhibitor 98.49% 否
HY-RS08606 MPC1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24967 Mpc1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18485 Mpc1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mpc1 NCBI NCBI:51660
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