2. Gene
  3. Nptn - neuroplastin Gene

Nptn - neuroplastin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: SDR-1; Sdfr1

基因 ID: 56064 | 基因类型: protein coding

关于 Nptn

功能概要

Enables cell adhesion molecule binding activity; transmembrane transporter binding activity; and type 1 Fibroblast Growth Factor receptor binding activity. Involved in several processes, including homophilic cell adhesion via plasma membrane adhesion molecules; positive regulation of signal transduction; and regulation of synaptic plasticity. Located in several cellular components, including inhibitory synapse; postsynaptic density; and presynaptic membrane. Is active in several cellular components, including GABA-ergic synapse; Schaffer collateral - CA1 synapse; and glutamatergic synapse. Is integral component of postsynaptic density membrane and integral component of presynaptic active zone membrane. Orthologous to human NPTN (neuroplastin). [provided by Alliance of Genome Resources, Apr 2022]

Nptn 基因产物(4)

mRNA Protein Name
NM_001413347.1 NP_001400276.1 neuroplastin isoform 1 precursor
NM_001413348.1 NP_001400277.1 neuroplastin isoform 3 precursor
NM_001413349.1 NP_001400278.1 neuroplastin isoform 4 precursor
NM_019380.3 NP_062253.1 neuroplastin isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cell adhesion molecule binding IDA
IDA: 通过直接分析推断
10759566 RGD
enables transmembrane transporter binding IPI
IPI: 通过物理相互作用推断
22389504 RGD
enables type 1 fibroblast growth factor receptor binding IDA
IDA: 通过直接分析推断
19952283 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in homophilic cell adhesion via plasma membrane adhesion molecules IDA
IDA: 通过直接分析推断
10759566 RGD
involved in long-term synaptic potentiation IDA
IDA: 通过直接分析推断
16925595 RGD
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
19952283 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
19952283 RGD
involved in positive regulation of fibroblast growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
19952283 RGD
involved in positive regulation of long-term neuronal synaptic plasticity IMP
IMP: 通过突变表型推断
10759566 RGD
involved in positive regulation of long-term synaptic potentiation IMP
IMP: 通过突变表型推断
10759566 RGD
involved in positive regulation of neuron projection development IDA
IDA: 通过直接分析推断
19952283 RGD
involved in positive regulation of protein localization IMP
IMP: 通过突变表型推断
22389504 RGD
involved in positive regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
16925595 RGD
involved in trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission EXP
EXP: 通过实验结果推断
10759566 RGD
involved in trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission IDA
IDA: 通过直接分析推断
10759566 RGD
involved in visual learning IDA
IDA: 通过直接分析推断
21480899 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse EXP
EXP: 通过实验结果推断
23622064 RGD
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
22389504 RGD
is active in Schaffer collateral - CA1 synapse EXP
EXP: 通过实验结果推断
10759566 RGD
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
10759566 RGD
located in cell surface IDA
IDA: 通过直接分析推断
10759566 RGD
located in dendrite IDA
IDA: 通过直接分析推断
22389504 RGD
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
23622064 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
23622064 RGD
located in inhibitory synapse IDA
IDA: 通过直接分析推断
22389504 RGD
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
3224275 RGD
is active in presynaptic active zone membrane EXP
EXP: 通过实验结果推断
23622064 RGD
is active in presynaptic active zone membrane IDA
IDA: 通过直接分析推断
23622064 RGD
located in presynaptic membrane IDA
IDA: 通过直接分析推断
11431460 RGD
is active in synaptic membrane IDA
IDA: 通过直接分析推断
22389504 RGD
located in synaptic membrane IDA
IDA: 通过直接分析推断
1573391 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neuroplastin

glycoprotein 55

glycoprotein 55/65

glycoprotein 65

gp55/65

stromal cell derived factor receptor 1

stromal cell-derived receptor 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09504 NPTN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19925 Nptn Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26427 Nptn Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nptn NCBI NCBI:27020
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