1. Gene
  2. Plek - pleckstrin Gene

Plek - pleckstrin Gene

种属: Mus musculus

同用名: 2010300B13Rik

基因 ID: 56193 | 基因类型: protein coding

关于 Plek

功能概要

Predicted to enable phosphatidylinositol-3,4-bisphosphate binding activity; protein homodimerization activity; and protein kinase C binding activity. Involved in several processes, including exocytosis; platelet aggregation; and positive regulation of cellular component organization. Predicted to be located in cytoplasm and ruffle membrane. Predicted to be active in plasma membrane. Orthologous to human PLEK (pleckstrin). [provided by Alliance of Genome Resources, Apr 2022]

Plek 基因产物(1)

mRNA Protein Name
NM_019549.2 NP_062422.1 pleckstrin
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
19190246 MGI
involved in platelet aggregation IMP
IMP: 通过突变表型推断
19190246 MGI
involved in positive regulation of actin filament depolymerization IMP
IMP: 通过突变表型推断
19190246 MGI
involved in positive regulation of integrin activation IMP
IMP: 通过突变表型推断
19190246 MGI
involved in positive regulation of platelet activation IMP
IMP: 通过突变表型推断
19190246 MGI
involved in protein secretion by platelet IMP
IMP: 通过突变表型推断
19190246 MGI
involved in thrombin-activated receptor signaling pathway IMP
IMP: 通过突变表型推断
19190246 MGI
involved in vesicle docking involved in exocytosis IMP
IMP: 通过突变表型推断
19190246 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

pleckstrin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Plek NCBI NCBI:5341