2. Gene
  3. Arl6 - ADP-ribosylation factor-like 6 Gene

Arl6 - ADP-ribosylation factor-like 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: BBS3; 1110018H24Rik; 2210411E14Rik

基因 ID: 56297 | 基因类型: protein coding

关于 Arl6

功能概要

Predicted to enable GTP binding activity. Involved in protein localization to non-motile cilium. Acts upstream of or within several processes, including fat cell differentiation; protein transport from ciliary membrane to plasma membrane; and retina layer formation. Located in cytosol and membrane. Is expressed in several structures, including central nervous system; chondrocranium; embryo endoderm; forelimb bud; and node. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 1; Bardet-Biedl syndrome 3; and retinitis pigmentosa 55. Orthologous to human ARL6 (ADP ribosylation factor like GTPase 6). [provided by Alliance of Genome Resources, Apr 2022]

Arl6 基因产物(2)

mRNA Protein Name
NM_001347244.1 NP_001334173.1 ADP-ribosylation factor-like protein 6 isoform 2
NM_019665.3 NP_062639.3 ADP-ribosylation factor-like protein 6 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10508919 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within brain development IMP
IMP: 通过突变表型推断
22139371 MGI
acts upstream of or within cilium assembly IMP
IMP: 通过突变表型推断
22139371 MGI
involved in fat cell differentiation IEP
IEP: 通过表达模式推断
17379567 MGI
involved in protein localization to non-motile cilium IDA
IDA: 通过直接分析推断
24939912 MGI
acts upstream of or within protein transport from ciliary membrane to plasma membrane IMP
IMP: 通过突变表型推断
22139371 MGI
acts upstream of or within regulation of smoothened signaling pathway IMP
IMP: 通过突变表型推断
22139371 MGI
acts upstream of or within retina layer formation IMP
IMP: 通过突变表型推断
20333246 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
10508919 MGI
located in cytosol IDA
IDA: 通过直接分析推断
22139371 MGI
located in membrane IDA
IDA: 通过直接分析推断
10508919 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ADP-ribosylation factor-like protein 6

ADP-ribosylation-like 6

ADP-ribosylation-like factor homolog ARL6

相关产品

Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00995 ARL6IP4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS00993 ARL6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS00994 ARL6IP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS00996 ARL6IP5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS00997 ARL6IP6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18720 Arl6ip6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20693 Arl6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21227 Arl6ip1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25207 Arl6ip6 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27204 Arl6 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27744 Arl6ip1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arl6 NCBI NCBI:84100
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