2. Gene
  3. Dbn1 - drebrin 1 Gene

Dbn1 - drebrin 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 56320 | 基因类型: protein coding

关于 Dbn1

功能概要

Predicted to enable actin filament binding activity; cytoskeletal motor inhibitor activity; and profilin binding activity. Involved in positive regulation of dendritic spine morphogenesis; positive regulation of receptor localization to synapse; and positive regulation of synaptic plasticity. Acts upstream of or within several processes, including cell communication by chemical coupling; cell communication by electrical coupling; and maintenance of protein location in cell. Located in several cellular components, including gap junction; glutamatergic synapse; and postsynaptic density. Is active in postsynaptic cytosol and postsynaptic membrane. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and retina. Orthologous to human DBN1 (drebrin 1). [provided by Alliance of Genome Resources, Apr 2022]

Dbn1 基因产物(3)

mRNA Protein Name
NM_001177371.1 NP_001170842.1 drebrin isoform 1
NM_001177372.1 NP_001170843.1 drebrin isoform 2
NM_019813.4 NP_062787.2 drebrin isoform 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15084279 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within actin filament organization IDA
IDA: 通过直接分析推断
11991718 MGI
acts upstream of or within cell communication by chemical coupling IMP
IMP: 通过突变表型推断
15084279 MGI
acts upstream of or within cell communication by electrical coupling IMP
IMP: 通过突变表型推断
15084279 MGI
involved in generation of neurons IEP
IEP: 通过表达模式推断
20882566 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
27996060 MGI
acts upstream of or within maintenance of protein location in cell IMP
IMP: 通过突变表型推断
15084279 MGI
involved in neural precursor cell proliferation IEP
IEP: 通过表达模式推断
20882566 MGI
involved in positive regulation of dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
25865831 MGI
involved in positive regulation of receptor localization to synapse IMP
IMP: 通过突变表型推断
25865831 MGI
involved in positive regulation of synaptic plasticity IMP
IMP: 通过突变表型推断
25865831 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
11991718 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
15084279 MGI
located in gap junction IDA
IDA: 通过直接分析推断
15084279 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
17559090 MGI
located in growth cone IDA
IDA: 通过直接分析推断
24720729 MGI
located in membrane IDA
IDA: 通过直接分析推断
15084279 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15084279 MGI
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
17559090 MGI
is active in postsynaptic density IDA
IDA: 通过直接分析推断
17559090 MGI
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
17559090 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

drebrin

developmentally-regulated brain protein

drebrin A

drebrin E2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03548 DBN1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21320 Dbn1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27839 Dbn1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dbn1 NCBI NCBI:1627
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