2. Gene
  3. Pus1 - pseudouridine synthase 1 Gene

Pus1 - pseudouridine synthase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: MPUS1; mPus1p; A730013B20Rik

基因 ID: 56361 | 基因类型: protein coding

关于 Pus1

功能概要

Enables chromatin binding activity; nuclear receptor coactivator activity; and tRNA pseudouridine synthase activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II and tRNA pseudouridine synthesis. Located in nucleolus. Part of transcription regulator complex. Used to study myopathy, lactic acidosis, and sideroblastic anemia. Human ortholog(s) of this gene implicated in myopathy, lactic acidosis, and sideroblastic anemia 1. Orthologous to human PUS1 (pseudouridine synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pus1 基因产物(6)

mRNA Protein Name
NM_001025561.3 NP_001020732.1 pseudouridylate synthase 1 homolog isoform 1
NM_001025562.2 NP_001020733.1 pseudouridylate synthase 1 homolog isoform 3
NM_001347390.1 NP_001334319.1 pseudouridylate synthase 1 homolog isoform 4
NM_001359218.1 NP_001346147.1 pseudouridylate synthase 1 homolog isoform 5
NM_001359219.1 NP_001346148.1 pseudouridylate synthase 1 homolog isoform 3
NM_019700.4 NP_062674.2 pseudouridylate synthase 1 homolog isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
15327771 MGI
enables nuclear receptor coactivator activity IDA
IDA: 通过直接分析推断
15327771 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15327771 MGI
enables pseudouridine synthase activity IDA
IDA: 通过直接分析推断
11027153 MGI
enables pseudouridine synthase activity IMP
IMP: 通过突变表型推断
15327771 MGI
enables tRNA pseudouridine synthase activity IDA
IDA: 通过直接分析推断
10094309 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15327771 MGI
acts upstream of or within tRNA pseudouridine synthesis IDA
IDA: 通过直接分析推断
11027153 MGI
involved in tRNA pseudouridine synthesis IDA
IDA: 通过直接分析推断
10094309 MGI
involved in tRNA pseudouridine synthesis IMP
IMP: 通过突变表型推断
27197761 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleolus IDA
IDA: 通过直接分析推断
15327771 MGI
is active in nucleus IDA
IDA: 通过直接分析推断
15327771 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15327771 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
15327771 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

pseudouridylate synthase 1 homolog

tRNA pseudouridine synthase A

tRNA pseudouridine synthase 1

tRNA pseudouridine synthase A, mitochondrial

tRNA pseudouridine(38-40) synthase

tRNA pseudouridylate synthase I

tRNA-uridine isomerase I

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11467 PUS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20804 Pus1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27318 Pus1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pus1 NCBI NCBI:80324
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