2. Gene
  3. Rbx1 - ring-box 1 Gene

Rbx1 - ring-box 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: ROC1; 1500002P15Rik

基因 ID: 56438 | 基因类型: protein coding

关于 Rbx1

功能概要

Predicted to enable cullin family protein binding activity; ubiquitin protein Ligase binding activity; and ubiquitin-like protein Ligase activity. Predicted to contribute to ubiquitin-protein transferase activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and protein ubiquitination. Acts upstream of or within protein K48-linked ubiquitination; protein catabolic process; and protein monoubiquitination. Located in cytosol. Part of SCF ubiquitin Ligase complex. Is expressed in several structures, including genitourinary system. Orthologous to human RBX1 (ring-box 1). [provided by Alliance of Genome Resources, Apr 2022]

Rbx1 基因产物(1)

mRNA Protein Name
NM_019712.3 NP_062686.1 E3 ubiquitin-protein ligase RBX1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14960280 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA damage response EXP
EXP: 通过实验结果推断
22118460 MGI
involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
12140560 MGI
involved in cellular response to UV EXP
EXP: 通过实验结果推断
22118460 MGI
acts upstream of or within protein K48-linked ubiquitination IDA
IDA: 通过直接分析推断
29593216 MGI
acts upstream of or within protein catabolic process IMP
IMP: 通过突变表型推断
15601820 MGI
acts upstream of or within protein monoubiquitination IGI
IGI: 通过遗传相互作用推断
21343341 MGI
involved in protein ubiquitination IDA
IDA: 通过直接分析推断
12140560 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Cul4A-RING E3 ubiquitin ligase complex EXP
EXP: 通过实验结果推断
22118460 MGI
part of SCF ubiquitin ligase complex IDA
IDA: 通过直接分析推断
12140560 MGI
part of SCF ubiquitin ligase complex IPI
IPI: 通过物理相互作用推断
16880526 MGI
located in cytosol IDA
IDA: 通过直接分析推断
12140560 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase RBX1

E3 ubiquitin-protein transferase RBX1

RING finger protein 75

ring-box protein 1

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-14658 Thalidomide Inducer 99.98% 是
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-14658S Thalidomide-d4 Inducer 98.00% 否
HY-RS11776 RBX1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18150 Rbx1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24625 Rbx1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rbx1 NCBI NCBI:9978
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