1. Gene
  2. IFNK - interferon kappa Gene

IFNK - interferon kappa Gene

中文名称:干扰素κ

种属: Homo sapiens

同用名: IFNT1; INFE1

基因 ID: 56832 | 基因类型: protein coding

关于 IFNK

Cytogenetic location: 9p21.2 Genomic coordinates (GRCh38): 9:27,524,290-27,526,498 (from NCBI)

This gene has 1 transcript (splice variant), 141 orthologues and 16 paralogues. Low expression observed in reference dataset.

功能概要

该基因编码 I 型干扰素家族的成员。 I 型干扰素是一组相关的糖蛋白,在宿主防御病毒感染中发挥重要作用。这种蛋白质在角质形成细胞中表达,该基因位于 9 号染色体上,与 I 型干扰素簇相邻。[RefSeq 提供,2008 年 7 月]

This gene encodes a member of the type I interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. This protein is expressed in keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster. [provided by RefSeq, Jul 2008]

IFNK 基因产物(1)

mRNA Protein Name
NM_020124.3 NP_064509.2 interferon kappa precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables type I interferon receptor binding IDA
IDA: 通过直接分析推断
11514542 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cytokine-mediated signaling pathway IDA
IDA: 通过直接分析推断
11514542 GOA
involved in regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
11514542 GOA
involved in response to virus IEP
IEP: 通过表达模式推断
11514542 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

IFNK 蛋白结构

Interferon

Interferon: Interferon alpha/beta domain (41 - 205)

  • 0
  • 100
  • 207 a.a.
蛋白主名 其他名称

interferon kappa

IFN-kappa

关联疾病

疾病名称 别名
Danubian Endemic Familial Nephropathy

Balkan Nephropathy

Balkan Endemic Nephropathy

Nephropathia Epidemica

Defn

Ben

Aristolochic Acid Nephropathy

Aan

Endemic Nephropathy Balkan

Balkan Nephritis

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus IFNK VGNC VGNC:62877
Canis familiaris IFNK VGNC VGNC:51739
Rattus norvegicus IFNK RGD RGD:1309045
Mus musculus IFNK MGD MGI:2683287
Bos taurus IFNK VGNC VGNC:30060