2. Gene
  3. LPAR5 - lysophosphatidic acid receptor 5 Gene

LPAR5 - lysophosphatidic acid receptor 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：溶血磷脂酸受体 5

种属: Homo sapiens

同用名: LPA5; GPR92; GPR93; KPG_010

基因 ID: 57121 | 基因类型: protein coding

关于 LPAR5

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:6,618,835-6,635,959 (from NCBI)

This gene has 3 transcripts (splice variants), 252 orthologues and 1 paralogue. Broad expression in colon (RPKM 5.6), lymph node (RPKM 4.4) and 23 other tissues.

功能概要

该基因编码 G 蛋白偶联跨膜受体的视紫红质类成员。这种蛋白质通过异三聚体 G 蛋白将细胞外信号从溶血磷脂酸传递到细胞，并介导许多细胞过程。许多 G 蛋白受体可作为药物的靶标。已经描述了该基因的转录变体。[RefSeq 提供，2008 年 12 月]

This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.[provided by RefSeq, Dec 2008]

LPAR5 基因产物(2)

mRNA Protein Name
NM_020400.6 NP_065133.1 lysophosphatidic acid receptor 5
NM_001142961.1 NP_001136433.1 lysophosphatidic acid receptor 5

LPAR5 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (40 - 297)

  • 0
  • 100
  • 200
  • 300
  • 372 a.a.
蛋白主名 其他名称

lysophosphatidic acid receptor 5

G protein-coupled receptor 92

G-protein coupled receptor 93

LPA receptor 5

LPA-5

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15706 H2L 5765834 Antagonist 98.66% 否
HY-114379 AS2717638 Antagonist 99.85% 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus LPAR5 RGD RGD:1562580
Macaca mulatta LPAR5 VGNC VGNC:74277
Canis familiaris LPAR5 VGNC VGNC:42746
Felis catus LPAR5 VGNC VGNC:82321
Mus musculus LPAR5 MGD MGI:2685918
Bos taurus LPAR5 VGNC VGNC:30959
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