2. Gene
  3. RHBG - Rh family B glycoprotein Gene

RHBG - Rh family B glycoprotein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：Rh 家族 B 糖蛋白

种属: Homo sapiens

同用名: SLC42A2

基因 ID: 57127 | 基因类型: protein coding

关于 RHBG

Cytogenetic location: 1q22 Genomic coordinates (GRCh38): 1:156,366,046-156,385,219 (from NCBI)

This gene has 9 transcripts (splice variants), 210 orthologues and 4 paralogues. Biased expression in kidney (RPKM 4.7), ovary (RPKM 3.9) and 5 other tissues.

功能概要

该基因编码恒河猴 (Rh) 蛋白家族的两个非红系成员之一。非红细胞 Rh 蛋白家族成员主要在肾脏中表达，属于甲基铵-铵通透酶/氨转运蛋白超家族。预计所有 Rh 家族蛋白都是跨膜蛋白，具有 12 个跨膜结构域和胞质内 N-和 C-末端。该基因的可变剪接导致多个转录变体。[RefSeq 提供，2012 年 1 月]

This gene encodes one of two non-erythroid members of the Rhesus (Rh) protein family. Non-erythroid Rh protein family members are mainly expressed in the kidney and belong to the methylammonium-ammonium permease/ammonia transporters superfamily. All Rh family proteins are predicted to be transmembrane proteins with 12 membrane spanning domains and intracytoplasmic N- and C-termini. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

RHBG 基因产物(6)

mRNA Protein Name
NM_001256395.2 NP_001243324.1 ammonium transporter Rh type B isoform b
NM_001256396.2 NP_001243325.1 ammonium transporter Rh type B isoform c
NM_001412175.1 NP_001399104.1 ammonium transporter Rh type B isoform d precursor
NM_001412176.1 NP_001399105.1 ammonium transporter Rh type B isoform e
NM_001412177.1 NP_001399106.1 ammonium transporter Rh type B isoform f
NM_020407.5 NP_065140.3 ammonium transporter Rh type B isoform a precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ammonium channel activity IDA
IDA: 通过直接分析推断
15929723 GOA
enables ankyrin binding IPI
IPI: 通过物理相互作用推断
15611082 GOA
enables carbon dioxide transmembrane transporter activity IDA
IDA: 通过直接分析推断
24077989 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ammonium transmembrane transport IDA
IDA: 通过直接分析推断
15929723 GOA
involved in transepithelial ammonium transport IDA
IDA: 通过直接分析推断
18032481 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
15611082 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
11024028 GOA
located in plasma membrane IMP
IMP: 通过突变表型推断
15611082 GOA
located in spectrin-associated cytoskeleton IMP
IMP: 通过突变表型推断
18635543 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RHBG 蛋白结构

Ammonium_transp

Ammonium_transp: Ammonium Transporter Family (26 - 417)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 441 a.a.
蛋白主名 其他名称

ammonium transporter Rh type B

Rhesus blood group, B glycoprotein

关联疾病

疾病名称 别名
Hemolytic Disease Of Fetus And Newborn, Rh-Induced

Rh Deficiency Syndrome

Rh Disease

HDFNRH

Rh Fetomaternal Incompatibility

Rh-Null Syndrome
Pseudohypoaldosteronism, Type I, Autosomal Recessive

Autosomal Recessive Pseudohypoaldosteronism Type 1

PHA1B

Pseudohypoaldosteronism Type 1

Pseudohypoaldosteronism, Type I

Generalized Pha1

Generalized Pseudohypoaldosteronism Type 1

Pseudohypoaldosteronism Type 1 Autosomal Recessive

Pha1

Pseudohypoaldosteronism

Pha I, Autosomal Recessive

Autosomal Recessive Pha 1

Pseudohypoaldosteronism Type 1, Recessive

Pseudohypoaldosteronism Type I

Autosomal Recessive Pha1

Pha Type 1

Pseudohypoaldosteronism 1, Autosomal Recessive

Multisystem Pseudohypoaldosteronism

Pha Type I, Autosomal Recessive

Pseudohypoaldosteronism Type I, Autosomal Recessive
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-176347S Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2 / 否
HY-RS11938 RHBG Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus RHBG VGNC VGNC:55671
Rattus norvegicus RHBG RGD RGD:727813
Mus musculus RHBG MGD MGI:1927379
Felis catus RHBG VGNC VGNC:99809
Macaca mulatta RHBG VGNC VGNC:99814
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