2. Gene
  3. CRACD - capping protein inhibiting regulator of actin dynamics Gene

CRACD - capping protein inhibiting regulator of actin dynamics Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：帽蛋白抑制肌动蛋白动力学调节器

种属: Homo sapiens

同用名: CRAD; KIAA1211

基因 ID: 57482 | 基因类型: protein coding

关于 CRACD

Cytogenetic location: 4q12 Genomic coordinates (GRCh38): 4:56,049,098-56,330,609 (from NCBI)

This gene has 10 transcripts (splice variants) and 177 orthologues. Biased expression in testis (RPKM 12.2), small intestine (RPKM 8.0) and 13 other tissues.

功能概要

参与倒刺末端肌动蛋白丝加帽的负调控。预测位于胞质溶胶中。 [由基因组资源联盟提供，2022 年 4 月]

Involved in negative regulation of barbed-end actin filament capping. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

CRACD 基因产物(6)

mRNA Protein Name
NM_001393381.1 NP_001380310.1 capping protein-inhibiting regulator of actin dynamics isoform 1
NM_001393382.1 NP_001380311.1 capping protein-inhibiting regulator of actin dynamics isoform 1
NM_001393383.1 NP_001380312.1 capping protein-inhibiting regulator of actin dynamics isoform 2
NM_001393384.1 NP_001380313.1 capping protein-inhibiting regulator of actin dynamics isoform 2
NM_001393385.1 NP_001380314.1 capping protein-inhibiting regulator of actin dynamics isoform 2
NM_020722.2 NP_065773.1 capping protein-inhibiting regulator of actin dynamics isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
30361697 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of barbed-end actin filament capping IDA
IDA: 通过直接分析推断
30361697 GOA
involved in positive regulation of actin filament polymerization IDA
IDA: 通过直接分析推断
30361697 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CRACD 蛋白结构

DUF4592

DUF4592: Domain of unknown function (DUF4592) (45 - 173)

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  • 1233 a.a.
蛋白主名 其他名称

capping protein-inhibiting regulator of actin dynamics

cancer-related regulator of actin dynamics

关联疾病

疾病名称 别名
Testicular Leydig Cell Tumor

Testicular Leydig Cell Neoplasm

Leydig Cell Tumor Of Testis

Interstitial Cell Neoplasm Of Testis
Testicular Sex Cord-Stromal Neoplasm

Sex Cord-Stromal Tumor Of Testis

Testicular Sex Cord-Stromal Tumor
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03136 CRACD Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CRACD RGD RGD:1311575
Macaca mulatta CRACD VGNC VGNC:73935
Mus musculus CRACD MGD MGI:2444817
Bos taurus CRACD VGNC VGNC:59341
Felis catus CRACD VGNC VGNC:63093
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