ARHGAP23 - Rho GTPase activating protein 23 Gene

中文名称：Rho GTP 酶激活蛋白 23

种属: Homo sapiens

关于 ARHGAP23

功能概要

RHO (参见 ARHA；MIM 165390) 小 GTP 酶家族通过跨膜受体参与信号转导，它们在 GDP 结合形式下不活跃，在 GTP 结合形式下活跃。 GTPase 激活蛋白，如 ARHGAP23，通过刺激 GTP 水解使 RHO 家族蛋白失活 (Katoh 和 Katoh，2004 [PubMed 15254754]) 。[OMIM 提供，2008 年 3 月]

The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008]