2. Gene
  3. SQOR - sulfide quinone oxidoreductase Gene

SQOR - sulfide quinone oxidoreductase Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：硫化物醌氧化还原酶

种属: Homo sapiens

同用名: SQR; SQRDL; CGI-44; PRO1975

基因 ID: 58472 | 基因类型: protein coding

关于 SQOR

Cytogenetic location: 15q21.1 Genomic coordinates (GRCh38): 15:45,631,148-45,691,281 (from NCBI)

This gene has 8 transcripts (splice variants), 222 orthologues and is associated with 1 phenotype. Broad expression in colon (RPKM 63.6), esophagus (RPKM 32.6) and 21 other tissues.

功能概要

由该基因编码的蛋白质可能在线粒体中发挥作用，催化硫化物转化为过硫化物，从而降低硫化物的毒性浓度。可变剪接导致编码相同蛋白质的多个转录变体。[RefSeq 提供，2012 年 9 月]

The protein encoded by this gene may function in mitochondria to catalyze the conversion of sulfide to persulfides, thereby decreasing toxic concencrations of sulfide. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2012]

SQOR 基因产物(2)

mRNA Protein Name
NM_001271213.2 NP_001258142.1 sulfide:quinone oxidoreductase, mitochondrial
NM_021199.4 NP_067022.1 sulfide:quinone oxidoreductase, mitochondrial
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glutathione-dependent sulfide quinone oxidoreductase activity IDA
IDA: 通过直接分析推断
25225291 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
33961781 GOA
enables sulfide:quinone oxidoreductase activity IDA
IDA: 通过直接分析推断
22852582 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in sulfide oxidation, using sulfide:quinone oxidoreductase IDA
IDA: 通过直接分析推断
22852582 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SQOR 蛋白结构

Pyr_redox_2

Pyr_redox_2: Pyridine nucleotide-disulphide oxidoreductase (46 - 339)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 450 a.a.
蛋白主名 其他名称

sulfide:quinone oxidoreductase, mitochondrial

sulfide dehydrogenase like

关联疾病

疾病名称 别名
Sulfide:Quinone Oxidoreductase Deficiency

SQORD

Sulfide Quinone Oxidoreductase Deficiency
Encephalopathy, Ethylmalonic

Ethylmalonic Encephalopathy

EE

Epema Syndrome

Encephalopathy, Petechiae, And Ethylmalonic Aciduria

Ethe1 Deficiency

Eme

Syndrome Of Encephalopathy, Petechiae, And Ethylmalonic Aciduria
Cystathioninuria

Cystathionase Deficiency

Gamma-Cystathionase Deficiency

Cystathione Gamma-Lyase Deficiency Syndrome

Cystathionine Gamma-Lyase Deficiency Syndrome

CSTNU
Leigh Syndrome

Leigh Disease

Infantile Subacute Necrotizing Encephalopathy

Leigh Syndrome Due To Mitochondrial Complex Iv Deficiency

LS

Sne

Leigh'S Disease

Leigh Syndrome Due To Mitochondrial Complex I Deficiency

Necrotizing Encephalopathy, Infantile Subacute, Of Leigh

Subacute Necrotizing Encephalomyelopathy

Necrotizing Encephalopathy Infantile Subacute Of Leigh

Leigh Syndrome Due To Mitochondrial Complex Iii Deficiency

Infantile Necrotizing Encephalomyelopathy

Juvenile Subacute Necrotizing Encephalomyelopathy

Leigh'S Necrotizing Encephalopathy

Subacute Necrotizing Encephalopathy

Juvenile Subacute Necrotizing Encephalopathy

Leigh Syndrome Due To Mitochondrial Complex Ii Deficiency

Leigh Syndrome Due To Mitochondrial Complex V Deficiency

Encephalopathy, Subacute Necrotizing, Infantile

Encephalopathy, Subacute Necrotizing, Juvenile

Maternally Inherited Leigh Syndrome

Subacute Necrotising Encephalomyelopathy

Subacute Necrotising Encephalopathy
Lactic Acidosis

Acidosis, Lactic

Acidosis Lactic
Interstitial Nephritis, Karyomegalic

Karyomegalic Interstitial Nephritis

KMIN

Kin

Systemic Karyomegaly

Karyomegalic Tubulointerstitial Nephritis

Ktn
Leber Congenital Amaurosis 1

LCA1

Amaurosis Congenita Of Leber I

Lca

Retinal Blindness, Congenital

Crb

Leber Congenital Amaurosis Type I

Leber Congenital Amaurosis, Type 1

Amaurosis Congenita Of Leber, Type 1
Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-144439 HTS07545 99.94% 否
HY-141552 FC9402 Inhibitor 99.61% 否
HY-RS13744 SQOR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17144 Sqor Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23591 Sqor Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SQOR RGD RGD:1564504
Bos taurus SQOR VGNC VGNC:101453
Macaca mulatta SQOR VGNC VGNC:99244
Mus musculus SQOR MGD MGI:1929899
Felis catus SQOR VGNC VGNC:101465
Canis familiaris SQOR VGNC VGNC:101445
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