2. Gene
  3. SRPRB - SRP receptor subunit beta Gene

SRPRB - SRP receptor subunit beta Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：SRP 受体亚基β

种属: Homo sapiens

同用名: APMCF1; SR-beta

基因 ID: 58477 | 基因类型: protein coding

关于 SRPRB

Cytogenetic location: 3q22.1 Genomic coordinates (GRCh38): 3:133,784,023-133,828,574 (from NCBI)

This gene has 6 transcripts (splice variants), 184 orthologues and 3 paralogues. Ubiquitous expression in thyroid (RPKM 18.4), testis (RPKM 17.1) and 25 other tissues.

功能概要

该基因编码的蛋白质与小鼠蛋白质具有相似性，后者是信号识别颗粒受体 (SR) 的一个亚基。该亚基是属于 GTPase 超家族的跨膜 GTPase。它将 α 亚基 (一种外周膜 GTP 酶) 锚定到 ER 膜上。 SR 是分泌蛋白和膜蛋白共翻译靶向 ER 膜所必需的。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane. [provided by RefSeq, Jul 2008]

SRPRB 基因产物(2)

mRNA Protein Name
NM_001379313.1 NP_001366242.1 signal recognition particle receptor subunit beta
NM_021203.4 NP_067026.3 signal recognition particle receptor subunit beta
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
19664239 GOA
located in cytoplasmic microtubule IDA
IDA: 通过直接分析推断
23264731 GOA
located in membrane IDA
IDA: 通过直接分析推断
22375059 GOA
part of signal recognition particle receptor complex EXP
EXP: 通过实验结果推断
16439358 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SRPRB 蛋白结构

SRPRB

SRPRB: Signal recognition particle receptor beta subunit (62 - 241)

  • 0
  • 100
  • 200
  • 271 a.a.
蛋白主名 其他名称

signal recognition particle receptor subunit beta

SRP receptor beta subunit

关联疾病

疾病名称 别名
Testis Seminoma

Seminoma Of Testis

Seminoma Testis

Testicular Seminoma Pure

Seminoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13781 SRPRB Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22830 Srprb Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29345 Srprb Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus SRPRB VGNC VGNC:102849
Mus musculus SRPRB MGD MGI:102964
Rattus norvegicus SRPRB RGD RGD:1304698
Macaca mulatta SRPRB VGNC VGNC:77980
Bos taurus SRPRB VGNC VGNC:35291
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