2. Gene
  3. Mefv - MEFV innate immunity regulator, pyrin Gene

Mefv - MEFV innate immunity regulator, pyrin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: pyrin

基因 ID: 58923 | 基因类型: protein coding

关于 Mefv

功能概要

Predicted to enable actin binding activity; identical protein binding activity; and ubiquitin protein Ligase activity. Involved in response to lipopolysaccharide and response to silicon dioxide. Predicted to be located in nucleus. Predicted to be part of microtubule associated complex. Predicted to be active in cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; Sweet syndrome; asthma; familial Mediterranean fever; and hematologic Cancer (multiple). Orthologous to human MEFV (MEFV innate immuity regulator, pyrin). [provided by Alliance of Genome Resources, Apr 2022]

Mefv 基因产物(1)

mRNA Protein Name
NM_031634.2 NP_113822.2 pyrin
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
16574623 RGD
involved in response to silicon dioxide IEP
IEP: 通过表达模式推断
16574623 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

pyrin

MEFV innate immuity regulator, pyrin

MEFV, pyrin innate immunity regulator

Mediterranean fever

marenostrin

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08313 MEFV Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20773 Mefv Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27287 Mefv Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mefv NCBI NCBI:4210
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