2. Gene
  3. Ghrl - ghrelin Gene

Ghrl - ghrelin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ghr; m46; MTLRP; MTLRPAP; 2210006E23Rik

基因 ID: 58991 | 基因类型: protein coding

关于 Ghrl

功能概要

This gene encodes a preproprotein that undergoes proteolytic processing to yield two bioactive peptides, ghrelin and obestatin. The hormone ghrelin plays a role in enhancing appetite and has numerous Other biological functions that include stimulating the secretion of growth hormone (somatotropin) from the anterior pituitary gland. Obestatin is thought to be a hormone that functions in decreasing appetite. Mice lacking the encoded protein develop normally and exhibit no gross anatomical abnormalities. This gene encodes distinct isoforms, some or all of which may undergo similar proteolytic processing. [provided by RefSeq, Jul 2016]

Ghrl 基因产物(5)

mRNA Protein Name
NM_001286404.1 NP_001273333.1 appetite-regulating hormone isoform 2 preproprotein
NM_001286405.1 NP_001273334.1 appetite-regulating hormone isoform 3 precursor
NM_001286406.1 NP_001273335.1 appetite-regulating hormone isoform 4 precursor
NM_001379129.1 NP_001366058.1 appetite-regulating hormone isoform 1 preproprotein
NM_021488.5 NP_067463.2 appetite-regulating hormone isoform 1 preproprotein
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adult feeding behavior IDA
IDA: 通过直接分析推断
16322794 MGI
acts upstream of or within dendrite development IMP
IMP: 通过突变表型推断
16491079 MGI
acts upstream of or within excitatory postsynaptic potential IMP
IMP: 通过突变表型推断
16491079 MGI
acts upstream of or within negative regulation of insulin secretion IMP
IMP: 通过突变表型推断
17130496 MGI
acts upstream of or within negative regulation of locomotion IMP
IMP: 通过突变表型推断
16322795 MGI
acts upstream of or within positive regulation of appetite IDA
IDA: 通过直接分析推断
15070777 MGI
involved in positive regulation of appetite IDA
IDA: 通过直接分析推断
16322794 MGI
acts upstream of or within positive regulation of appetite IGI
IGI: 通过遗传相互作用推断
15070777 MGI
NOT acts upstream of or within positive regulation of appetite IMP
IMP: 通过突变表型推断
14585959 MGI
acts upstream of or within positive regulation of appetite IMP
IMP: 通过突变表型推断
17060947 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
19666521 MGI
acts upstream of or within positive regulation of synapse assembly IMP
IMP: 通过突变表型推断
16491079 MGI
acts upstream of synapse assembly IMP
IMP: 通过突变表型推断
16491079 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
10930375 MGI
located in extracellular region IDA
IDA: 通过直接分析推断
10930375 MGI
is active in neuronal dense core vesicle lumen IDA
IDA: 通过直接分析推断
12597862 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

appetite-regulating hormone

growth hormone secretagogue

growth hormone-releasing peptide

motilin-related peptide

preproghrelin

proghrelin

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05415 GHRL Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20741 Ghrl Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27253 Ghrl Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ghrl NCBI NCBI:51738
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