2. Gene
  3. Pdzk1 - PDZ domain containing 1 Gene

Pdzk1 - PDZ domain containing 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Pdzd1; Nherf3; mPDZK1; NHERF-3; naPi-Cap1; D3Ertd537e; 1700023D20Rik; 2610507N21Rik; 4921513F16Rik

基因 ID: 59020 | 基因类型: protein coding

关于 Pdzk1

功能概要

Predicted to enable PDZ domain binding activity; protein-membrane adaptor activity; and scavenger receptor binding activity. Involved in positive regulation of protein targeting to membrane; protein localization to plasma membrane; and regulation of anion transport. Acts upstream of or within in utero embryonic development. Located in brush border membrane. Is expressed in several structures, including genitourinary system; liver; trunk; and white fat. Orthologous to human PDZK1 (PDZ domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Pdzk1 基因产物(3)

mRNA Protein Name
NM_001146001.2 NP_001139473.1 Na(+)/H(+) exchange regulatory cofactor NHE-RF3
NM_001355710.1 NP_001342639.1 Na(+)/H(+) exchange regulatory cofactor NHE-RF3
NM_021517.3 NP_067492.2 Na(+)/H(+) exchange regulatory cofactor NHE-RF3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14531806 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
27996060 MGI
involved in positive regulation of protein targeting to membrane IMP
IMP: 通过突变表型推断
16141316 MGI
involved in protein localization to plasma membrane IMP
IMP: 通过突变表型推断
17990980 MGI
involved in regulation of monoatomic anion transport IMP
IMP: 通过突变表型推断
16141316 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in brush border membrane IDA
IDA: 通过直接分析推断
15523054 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
16141316 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

Na(+)/H(+) exchange regulatory cofactor NHE-RF3

CFTR-associated protein of 70 kDa

Na(+)/H(+) exchanger regulatory factor 3

PDZ domain-containing protein 1

na/Pi cotransporter C-terminal-associated protein 1

sodium-hydrogen exchanger regulatory factor 3

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10305 PDZK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS10306 PDZK1IP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20077 Pdzk1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21275 Pdzk1ip1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26580 Pdzk1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pdzk1 NCBI NCBI:5174
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