2. Gene
  3. Grk6 - G protein-coupled receptor kinase 6 Gene

Grk6 - G protein-coupled receptor kinase 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Gprk6

基因 ID: 59076 | 基因类型: protein coding

关于 Grk6

功能概要

Enables G protein-coupled receptor kinase activity. Involved in several processes, including cellular response to lipopolysaccharide; desensitization of G protein-coupled receptor signaling pathway; and negative regulation of anion channel activity. Located in cytosol and plasma membrane. Biomarker of Parkinson's disease. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human GRK6 (G protein-coupled receptor kinase 6). [provided by Alliance of Genome Resources, Apr 2022]

Grk6 基因产物(3)

mRNA Protein Name
NM_001112712.2 NP_001106183.1 G protein-coupled receptor kinase 6 isoform c
NM_001112713.1 NP_001106184.1 G protein-coupled receptor kinase 6 isoform b
NM_031657.4 NP_113845.2 G protein-coupled receptor kinase 6 isoform a
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor kinase activity IDA
IDA: 通过直接分析推断
12810562 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
23359120 RGD
involved in desensitization of G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
12810562 RGD
involved in desensitization of G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
17908240 RGD
involved in negative regulation of anion channel activity IMP
IMP: 通过突变表型推断
17170521 RGD
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
12810562 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

G protein-coupled receptor kinase 6

g protein-coupled receptor kinase GRK6

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-128231 GRK6-IN-4 Inhibitor / Phase 1
Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-142812 GRK6-IN-1 99.61% 否
HY-142817 GRK6-IN-2 98.98% 否
HY-128311 GRK6-IN-3 Inhibitor / 否
HY-150021 GRK5-IN-3 Inhibitor / 否
HY-RS05817 GRK6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-159996 GRL093-22 Inhibitor / 否
HY-169678 GRK6-IN-5 Inhibitor / 否
HY-174256 GRL-098-22 Inhibitor / 否
HY-RS17369 Grk6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23823 Grk6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Grk6 NCBI NCBI:2870
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