1. Gene
  2. Grk4 - G protein-coupled receptor kinase 4 Gene

Grk4 - G protein-coupled receptor kinase 4 Gene

种属: Rattus norvegicus

同用名: Gprk2l

基因 ID: 59077 | 基因类型: protein coding

关于 Grk4

功能概要

Enables rhodopsin kinase activity. Involved in G protein-coupled receptor internalization and protein phosphorylation. Located in cytosol; dendrite; and neuronal cell body. Human ortholog(s) of this gene implicated in essential hypertension. Orthologous to human GRK4 (G protein-coupled receptor kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Grk4 基因产物(1)

mRNA Protein Name
NM_022928.1 NP_075217.1 G protein-coupled receptor kinase 4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables rhodopsin kinase activity IDA
IDA: 通过直接分析推断
9607785 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled receptor internalization IMP
IMP: 通过突变表型推断
12519791 RGD
involved in desensitization of G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
15166006 RGD
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
9607785 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendrite IDA
IDA: 通过直接分析推断
11099476 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
11099476 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

G protein-coupled receptor kinase 4

G protein-coupled receptor kinase 2, groucho gene related

g protein-coupled receptor kinase GRK4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Grk4 NCBI NCBI:2868