1. Gene
  2. Ptges - prostaglandin E synthase Gene

Ptges - prostaglandin E synthase Gene

种属: Rattus norvegicus

同用名: Pges; mPGES-1

基因 ID: 59103 | 基因类型: protein coding

关于 Ptges

功能概要

Enables prostaglandin-D synthase activity and prostaglandin-E synthase activity. Involved in several processes, including prostaglandin biosynthetic process; response to lipopolysaccharide; and response to retinoic acid. Located in intracellular membrane-bounded organelle and perinuclear region of cytoplasm. Biomarker of Barrett's esophagus; ischemia; papilloma; peptic esophagitis; and transitional cell carcinoma. Orthologous to human PTGES (prostaglandin E synthase). [provided by Alliance of Genome Resources, Apr 2022]

Ptges 基因产物(1)

mRNA Protein Name
NM_021583.3 NP_067594.1 prostaglandin E synthase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables prostaglandin-D synthase activity IDA
IDA: 通过直接分析推断
10869354 RGD
enables prostaglandin-E synthase activity IDA
IDA: 通过直接分析推断
11067848 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chronic inflammatory response IEP
IEP: 通过表达模式推断
12707354 RGD
involved in prostaglandin biosynthetic process IDA
IDA: 通过直接分析推断
11067848 RGD
involved in response to calcium ion IEP
IEP: 通过表达模式推断
16598755 RGD
involved in response to cytokine IEP
IEP: 通过表达模式推断
16816110 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
18383341 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
17927823 RGD
involved in response to retinoic acid IEP
IEP: 通过表达模式推断
18183617 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
15284079 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

prostaglandin E synthase

glutathione peroxidase PTGES

glutathione transferase PTGES

inducible prostaglandin E synthase

microsomal prostaglandin E synthase 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptges NCBI NCBI:9536