2. Gene
  3. Ago2 - argonaute RISC catalytic component 2 Gene

Ago2 - argonaute RISC catalytic component 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Eif2c2; eIF2C 2

基因 ID: 59117 | 基因类型: protein coding

关于 Ago2

功能概要

Predicted to enable several functions, including endoribonuclease activity, producing 5'-phosphomonoesters; nucleic acid binding activity; and protein C-terminus binding activity. Involved in negative regulation of amyloid precursor protein biosynthetic process. Located in mitochondrion. Orthologous to human AGO2 (argonaute RISC catalytic component 2). [provided by Alliance of Genome Resources, Apr 2022]

Ago2 基因产物(1)

mRNA Protein Name
NM_001408918.1 NP_001395847.1 protein argonaute-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Hsp70 protein binding IDA
IDA: 通过直接分析推断
11553639 RGD
enables Hsp90 protein binding IDA
IDA: 通过直接分析推断
11553639 RGD
enables RISC complex binding IDA
IDA: 通过直接分析推断
30404558 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
24882364 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to calcium ion IEP
IEP: 通过表达模式推断
28404816 RGD
involved in negative regulation of amyloid precursor protein biosynthetic process IMP
IMP: 通过突变表型推断
20395292 RGD
involved in positive regulation of post-transcriptional gene silencing by RNA IMP
IMP: 通过突变表型推断
15147961 RGD
involved in regulation of mRNA stability IMP
IMP: 通过突变表型推断
26846850 RGD
involved in response to cocaine IEP
IEP: 通过表达模式推断
26944283 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
21969601 RGD
involved in response to morphine IEP
IEP: 通过表达模式推断
23927484 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
27029769 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
11553639 RGD
located in P granule IDA
IDA: 通过直接分析推断
27029769 RGD
part of RISC complex IDA
IDA: 通过直接分析推断
30404558 RGD
located in chromatoid body IDA
IDA: 通过直接分析推断
27029769 RGD
located in cytoplasm IDA
IDA: 通过直接分析推断
27029769 RGD
located in cytoplasmic stress granule IDA
IDA: 通过直接分析推断
30404558 RGD
located in cytosol IDA
IDA: 通过直接分析推断
27029769 RGD
located in dendrite IDA
IDA: 通过直接分析推断
28404816 RGD
located in membrane IDA
IDA: 通过直接分析推断
11553639 RGD
located in mitochondrion IDA
IDA: 通过直接分析推断
22518031 RGD
located in pi-body IDA
IDA: 通过直接分析推断
27029769 RGD
part of ribonucleoprotein complex IDA
IDA: 通过直接分析推断
23041308 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein argonaute-2

argonaute 2, RISC catalytic component

argonaute2

eukaryotic translation initiation factor 2C 2

golgi ER protein 95 kDa

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-119024 BCI-137 99.55% 否
HY-RS00453 AGO2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17683 Ago2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24144 Ago2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ago2 NCBI NCBI:27161
Mus musculus Ago2 NCBI NCBI:239528
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