1. Gene
  2. Ereg - epiregulin Gene

Ereg - epiregulin Gene

种属: Rattus norvegicus

基因 ID: 59325 | 基因类型: protein coding

关于 Ereg

功能概要

Enables growth factor activity. Involved in several processes, including female gamete generation; positive regulation of macromolecule metabolic process; and positive regulation of mitotic nuclear division. Located in extracellular space. Human ortholog(s) of this gene implicated in extrapulmonary tuberculosis; pulmonary tuberculosis; and tuberculosis. Orthologous to human EREG (Epiregulin). [provided by Alliance of Genome Resources, Apr 2022]

Ereg 基因产物(1)

mRNA Protein Name
NM_021689.1 NP_067721.1 proepiregulin preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables growth factor activity IDA
IDA: 通过直接分析推断
9990076 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in epidermal growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
9990076 RGD
involved in female meiotic nuclear division IDA
IDA: 通过直接分析推断
15459120 RGD
involved in luteinizing hormone signaling pathway IDA
IDA: 通过直接分析推断
15459120 RGD
involved in oocyte maturation IDA
IDA: 通过直接分析推断
15459120 RGD
involved in ovarian cumulus expansion IDA
IDA: 通过直接分析推断
15459120 RGD
involved in ovulation IDA
IDA: 通过直接分析推断
15459120 RGD
involved in positive regulation of DNA replication IDA
IDA: 通过直接分析推断
9990076 RGD
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
9990076 RGD
involved in positive regulation of mitotic nuclear division IDA
IDA: 通过直接分析推断
9990076 RGD
involved in positive regulation of smooth muscle cell proliferation IDA
IDA: 通过直接分析推断
9990076 RGD
involved in positive regulation of smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
14570897 RGD
involved in primary follicle stage IDA
IDA: 通过直接分析推断
15459120 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
15459120 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
14570897 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

proepiregulin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ereg NCBI NCBI:2069
Mus musculus Ereg NCBI NCBI:13874