1. Gene
  2. Twist2 - twist family bHLH transcription factor 2 Gene

Twist2 - twist family bHLH transcription factor 2 Gene

种属: Rattus norvegicus

同用名: Dermo1

基因 ID: 59327 | 基因类型: protein coding

关于 Twist2

功能概要

Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in negative regulation of apoptotic process. Predicted to be located in cytoplasm; nucleolus; and nucleoplasm. Predicted to be part of transcription regulator complex. Human ortholog(s) of this gene implicated in Barber-Say syndrome; ablepharon macrostomia syndrome; and focal dermal hypoplasia. Orthologous to human TWIST2 (twist family bHLH transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Twist2 基因产物(1)

mRNA Protein Name
NM_021691.2 NP_067723.1 twist-related protein 2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of apoptotic process IDA
IDA: 通过直接分析推断
10485844 RGD
involved in response to insulin IEP
IEP: 通过表达模式推断
20818503 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
20818503 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

twist-related protein 2

dermo-1 protein

twist basic helix-loop-helix transcription factor 2

twist homolog 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Twist2 NCBI NCBI:117581