1. Gene
  2. RBP2 - retinol binding protein 2 Gene

RBP2 - retinol binding protein 2 Gene

中文名称:视黄醇结合蛋白 2

种属: Homo sapiens

同用名: CRBP2; RBPC2; CRBPII; CRABP-II

基因 ID: 5948 | 基因类型: protein coding

关于 RBP2

Cytogenetic location: 3q23 Genomic coordinates (GRCh38): 3:139,452,884-139,476,516 (from NCBI)

This gene has 3 transcripts (splice variants), 249 orthologues and 15 paralogues. Biased expression in duodenum (RPKM 1065.7) and small intestine (RPKM 769.4).

功能概要

该基因编码存在于小肠上皮细胞中的丰富蛋白质。它被认为参与维生素 A 的摄取和/或细胞内代谢。维生素 A 是生长、繁殖、上皮组织分化和视觉所必需的脂溶性维生素。这种蛋白质还可以调节月经周期中视黄酸对子宫内膜细胞核的供应。[RefSeq 提供,2015 年 8 月]

This gene encodes an abundant protein present in the small intestinal epithelium. It is thought to participate in the uptake and/or intracellular metabolism of vitamin A. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. This protein may also modulate the supply of retinoic acid to the nuclei of endometrial cells during the menstrual cycle. [provided by RefSeq, Aug 2015]

RBP2 基因产物(1)

mRNA Protein Name
NM_004164.3 NP_004155.2 retinol-binding protein 2

RBP2 蛋白结构

Lipocalin

Lipocalin: Lipocalin / cytosolic fatty-acid binding protein family (6 - 133)

  • 0
  • 100
  • 134 a.a.
蛋白主名 其他名称

retinol-binding protein 2

CRBP-II

重组 RBP2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71249 RBP2 Protein, Human P50120 (M1-K134) ≥95%

关联疾病

疾病名称 别名
Hypervitaminosis A

Hypervitaminosis A, Susceptibility To

Hyperalimentation Of Vitamin A

Diaphragmatic Hernia, Congenital

Congenital Diaphragmatic Hernia

Diaphragmatic Hernia

Cdh

Congenital Diaphragmatic Defect

Hernia, Diaphragmatic

Dih

Hernia, Congenital Diaphragmatic

Hcd

Diaphragmatic Defect, Congenital

Diaphragm, Unilateral Agenesis Of

Hemidiaphragm, Agenesis Of

Diaphragmatic Hernia 1

Agenesis Of Hemidiaphragm

Unilateral Agenesis Of Diaphragm

Hernia Diaphragmatic

Hernia Diaphragmatic Congenital

Hernia, Diaphragmatic, Type 1

Hiatus Hernia

Oesophageal Hiatus Hernia

Paraoesophageal Hernia

Sliding Hiatus Hernia

Congenital Diaphragm Hernia

Congenital Diaphragm Defect With Hernia

Gross Congenital Diaphragm Defect

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris RBP2 VGNC VGNC:45430
Felis catus RBP2 VGNC VGNC:69272
Bos taurus RBP2 VGNC VGNC:33813
Macaca mulatta RBP2 VGNC VGNC:110345
Rattus norvegicus RBP2 RGD RGD:3544
Mus musculus RBP2 MGD MGI:97877
Others RBP2 NCBI