2. Gene
  3. Syne1 - spectrin repeat containing, nuclear envelope 1 Gene

Syne1 - spectrin repeat containing, nuclear envelope 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 8B; CPG2; KASH1; Myne1; myne-1; mKIAA1756; A330049M09Rik; C130039F11Rik

基因 ID: 64009 | 基因类型: protein coding

关于 Syne1

功能概要

Enables actin filament binding activity and protein homodimerization activity. Involved in centrosome localization and regulation of cilium assembly. Acts upstream of or within nuclear migration. Located in nuclear envelope. Is expressed in several structures, including alimentary system; ear; genitourinary system; musculoskeletal system; and nervous system. Used to study Emery-Dreifuss muscular dystrophy. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita (multiple); bipolar disorder; cerebellar ataxia (multiple); and muscular dystrophy (multiple). Orthologous to human SYNE1 (spectrin repeat containing nuclear envelope protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Syne1 基因产物(5)

mRNA Protein Name
NM_001079686.1 NP_001073154.1 nesprin-1 isoform 3
NM_001347711.1 NP_001334640.1 nesprin-1 isoform 4
NM_001347732.1 NP_001334661.1 nesprin-1 isoform 5
NM_022027.2 NP_071310.2 nesprin-1 isoform 2
NM_153399.2 NP_700448.2 nesprin-1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin filament binding IMP
IMP: 通过突变表型推断
22518138 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
22518138 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10878022 MGI
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
22518138 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in centrosome localization IMP
IMP: 通过突变表型推断
19596800 MGI
acts upstream of or within nuclear migration IMP
IMP: 通过突变表型推断
17267447 MGI
involved in regulation of cilium assembly IMP
IMP: 通过突变表型推断
19596800 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nuclear envelope IDA
IDA: 通过直接分析推断
10878022 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nesprin-1

KASH domain-containing protein 1

enaptin

enaptin165

myocyte nuclear envelope protein 1

nesprin 1

nuclear envelope spectrin repeat protein 1

synaptic nuclear envelope 1

synaptic nuclear envelope protein 1

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14085 SYNE1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22841 Syne1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Syne1 NCBI NCBI:23345
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z