1. Gene
  2. Ccnd2 - cyclin D2 Gene

Ccnd2 - cyclin D2 Gene

种属: Rattus norvegicus

基因 ID: 64033 | 基因类型: protein coding

关于 Ccnd2

功能概要

Enables protein kinase binding activity. Involved in several processes, including cellular response to Insulin stimulus; response to estradiol; and response to testosterone. Predicted to be located in chromatin; cytosol; and nucleus. Predicted to be part of cyclin D2-CDK4 complex. Predicted to be active in cytoplasm and nucleus. Used to study transitional cell carcinoma. Biomarker of colon cancer; glaucoma; impotence; and nephritis. Human ortholog(s) of this gene implicated in ductal carcinoma in situ; invasive lobular carcinoma; prostate cancer; and transitional cell carcinoma. Orthologous to human CCND2 (cyclin D2). [provided by Alliance of Genome Resources, Apr 2022]

Ccnd2 基因产物(1)

mRNA Protein Name
NM_022267.2 NP_071603.2 G1/S-specific cyclin-D2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
15809057 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G1/S transition of mitotic cell cycle IEP
IEP: 通过表达模式推断
7926809 RGD
involved in G1/S transition of mitotic cell cycle IMP
IMP: 通过突变表型推断
12130558 RGD
involved in cellular response to dexamethasone stimulus IEP
IEP: 通过表达模式推断
27302109 RGD
involved in cellular response to follicle-stimulating hormone stimulus IEP
IEP: 通过表达模式推断
15613482 RGD
involved in cellular response to growth hormone stimulus IEP
IEP: 通过表达模式推断
12586844 RGD
involved in cellular response to insulin stimulus IEP
IEP: 通过表达模式推断
16210359 RGD
involved in cellular response to testosterone stimulus IEP
IEP: 通过表达模式推断
23028064 RGD
involved in liver development IEP
IEP: 通过表达模式推断
15809057 RGD
involved in negative regulation of cardiac muscle cell differentiation IDA
IDA: 通过直接分析推断
27302109 RGD
involved in ovarian follicle development IEP
IEP: 通过表达模式推断
17971845 RGD
involved in positive regulation of cardiac muscle cell proliferation IDA
IDA: 通过直接分析推断
27302109 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
12130558 RGD
involved in positive regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
7811475 RGD
involved in regulation of neuron differentiation IEP
IEP: 通过表达模式推断
8028782 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
9658398 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
12437973 RGD
involved in response to estrogen IEP
IEP: 通过表达模式推断
9658398 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
12480138 RGD
involved in response to follicle-stimulating hormone IEP
IEP: 通过表达模式推断
9658398 RGD
involved in response to human chorionic gonadotropin IEP
IEP: 通过表达模式推断
9658398 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
7811475 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
14691013 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
15659706 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
15659706 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

G1/S-specific cyclin-D2

vin-1 proto-oncogene

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccnd2 NCBI NCBI:894