2. Gene
  3. ACOT1 - acyl-CoA thioesterase 1 Gene

ACOT1 - acyl-CoA thioesterase 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：酰基辅酶 A 硫酯酶 1

种属: Homo sapiens

同用名: ACH2; CTE-1; LACH2

基因 ID: 641371 | 基因类型: protein coding

关于 ACOT1

Cytogenetic location: 14q24.3 Genomic coordinates (GRCh38): 14:73,490,933-73,543,796 (from NCBI)

This gene has 2 transcripts (splice variants), 436 orthologues and 4 paralogues. Broad expression in fat (RPKM 27.2), liver (RPKM 24.9) and 24 other tissues.

功能概要

启用酰基辅酶 A 水解酶活性。参与酰基辅酶 A 代谢过程；长链脂肪酸代谢过程；以及非常长链的脂肪酸代谢过程。位于胞质溶胶中。 [由基因组资源联盟提供，2022 年 4 月]

Enables acyl-CoA hydrolase activity. Involved in acyl-CoA metabolic process; long-chain fatty acid metabolic process; and very long-chain fatty acid metabolic process. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

ACOT1 基因产物(1)

mRNA Protein Name
NM_001037161.2 NP_001032238.1 acyl-coenzyme A thioesterase 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fatty acyl-CoA hydrolase activity IDA
IDA: 通过直接分析推断
16940157 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acyl-CoA metabolic process IDA
IDA: 通过直接分析推断
16940157 GOA
involved in long-chain fatty acid metabolic process IDA
IDA: 通过直接分析推断
16940157 GOA
involved in very long-chain fatty acid metabolic process IDA
IDA: 通过直接分析推断
16940157 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
16940157 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ACOT1 蛋白结构

Bile_Hydr_Trans

Bile_Hydr_Trans: Acyl-CoA thioester hydrolase/BAAT N-terminal region (15 - 141)

BAAT_C

BAAT_C: BAAT / Acyl-CoA thioester hydrolase C terminal (204 - 411)

  • 0
  • 100
  • 200
  • 300
  • 421 a.a.
蛋白主名 其他名称

acyl-coenzyme A thioesterase 1

CTE-I

关联疾病

疾病名称 别名
Aztreonam Allergy

Azactam Allergy

Primbactam Allergy
Cefaclor Allergy

Ceclor Allergy

Cephaclor Allergy
Cefuroxime Allergy

Cephuroxime Allergy

Zinacef Allergy
Ceftriaxone Allergy

Rocephin Allergy
Anorectal Stricture

Stenosis Of Rectum And Anus

Anorectal Malformations
Mitochondrial Pyruvate Carrier Deficiency

MPYCD
Pitt-Hopkins-Like Syndrome 2

PTHSL2

Mesh

D006985

Mesh

D008607
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00173 ACOT1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21470 Acot1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27988 Acot1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ACOT1 RGD RGD:70894
Mus musculus ACOT1 MGD MGI:1349396
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