1. Gene
  2. Ascl1 - achaete-scute family bHLH transcription factor 1 Gene

Ascl1 - achaete-scute family bHLH transcription factor 1 Gene

种属: Rattus norvegicus

同用名: Mash1

基因 ID: 64186 | 基因类型: protein coding

关于 Ascl1

功能概要

Enables double-stranded DNA binding activity and identical protein binding activity. Involved in several processes, including cellular response to magnetism; regulation of neuron differentiation; and response to epidermal growth factor. Predicted to be located in neuronal cell body and nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Biomarker of status epilepticus. Orthologous to human ASCL1 (achaete-scute family bHLH transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ascl1 基因产物(1)

mRNA Protein Name
NM_022384.2 NP_071779.1 achaete-scute homolog 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
9521744 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
9521744 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to magnetism IEP
IEP: 通过表达模式推断
19382241 RGD
involved in forebrain neuron differentiation IDA
IDA: 通过直接分析推断
17936272 RGD
involved in heart development IEP
IEP: 通过表达模式推断
11803116 RGD
involved in negative regulation of neuron differentiation IDA
IDA: 通过直接分析推断
17936272 RGD
involved in nervous system development IDA
IDA: 通过直接分析推断
11923194 RGD
involved in positive regulation of neuron differentiation IDA
IDA: 通过直接分析推断
10648228 RGD
involved in response to epidermal growth factor IEP
IEP: 通过表达模式推断
9473334 RGD
involved in response to folic acid IEP
IEP: 通过表达模式推断
19001765 RGD
involved in response to retinoic acid IEP
IEP: 通过表达模式推断
11803116 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

achaete-scute homolog 1

achaete-scute complex homolog 1

achaete-scute complex homolog-like 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ascl1 NCBI NCBI:429