1. Gene
  2. Qdpr - quinoid dihydropteridine reductase Gene

Qdpr - quinoid dihydropteridine reductase Gene

种属: Rattus norvegicus

基因 ID: 64192 | 基因类型: protein coding

关于 Qdpr

功能概要

Enables 6,7-dihydropteridine reductase activity; identical protein binding activity; and nucleotide binding activity. Involved in several processes, including L-phenylalanine catabolic process; response to glucagon; and tetrahydrobiopterin biosynthetic process. Located in cytosol and neuron projection. Biomarker of hypertension and status epilepticus. Human ortholog(s) of this gene implicated in phenylketonuria. Orthologous to human QDPR (quinoid dihydropteridine reductase). [provided by Alliance of Genome Resources, Apr 2022]

Qdpr 基因产物(1)

mRNA Protein Name
NM_022390.2 NP_071785.1 dihydropteridine reductase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 6,7-dihydropteridine reductase activity IDA
IDA: 通过直接分析推断
660556 RGD
enables 6,7-dihydropteridine reductase activity IMP
IMP: 通过突变表型推断
1898002 RGD
enables NADH binding IPI
IPI: 通过物理相互作用推断
8631945 RGD
enables NADPH binding IMP
IMP: 通过突变表型推断
1639779 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
1631094 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in L-phenylalanine catabolic process IEP
IEP: 通过表达模式推断
4155291 RGD
involved in cellular response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
2484967 RGD
involved in liver development IEP
IEP: 通过表达模式推断
710385 RGD
involved in response to aluminum ion IEP
IEP: 通过表达模式推断
3477172 RGD
involved in response to glucagon IEP
IEP: 通过表达模式推断
4155291 RGD
involved in response to lead ion IEP
IEP: 通过表达模式推断
3815851 RGD
involved in tetrahydrobiopterin biosynthetic process IDA
IDA: 通过直接分析推断
660556 RGD
involved in tetrahydrobiopterin biosynthetic process IMP
IMP: 通过突变表型推断
1898002 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

dihydropteridine reductase

HDHPR

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Qdpr NCBI NCBI:5860