1. Gene
  2. Tdo2 - tryptophan 2,3-dioxygenase Gene

Tdo2 - tryptophan 2,3-dioxygenase Gene

种属: Rattus norvegicus

同用名: TO; Tdo

基因 ID: 64206 | 基因类型: protein coding

关于 Tdo2

功能概要

Enables several functions, including heme binding activity; oxygen binding activity; and tryptophan 2,3-dioxygenase activity. Involved in response to nitroglycerin and tryptophan catabolic process to acetyl-CoA. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Orthologous to human TDO2 (tryptophan 2,3-dioxygenase). [provided by Alliance of Genome Resources, Apr 2022]

Tdo2 基因产物(1)

mRNA Protein Name
NM_022403.2 NP_071798.1 tryptophan 2,3-dioxygenase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables amino acid binding IDA
IDA: 通过直接分析推断
3899109 RGD
enables heme binding IDA
IDA: 通过直接分析推断
3400092 RGD
enables oxygen binding IDA
IDA: 通过直接分析推断
10719243 RGD
enables tryptophan 2,3-dioxygenase activity IDA
IDA: 通过直接分析推断
3400092 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to nitroglycerin IEP
IEP: 通过表达模式推断
28659861 RGD
involved in tryptophan catabolic process to acetyl-CoA IDA
IDA: 通过直接分析推断
7236232 RGD
involved in tryptophan metabolic process IDA
IDA: 通过直接分析推断
3400092 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

tryptophan 2,3-dioxygenase

TRPO

tryptamin 2,3-dioxygenase

tryptophan 2,3-dioxygenase A

tryptophan oxygenase

tryptophan pyrrolase

tryptophan-23-dioxygenase

tryptophanase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tdo2 NCBI NCBI:6999