1. Gene
  2. Ptges - prostaglandin E synthase Gene

Ptges - prostaglandin E synthase Gene

种属: Mus musculus

同用名: Pges; mPGES; mPGES-1; D2Ertd369e; 2410099E23Rik

基因 ID: 64292 | 基因类型: protein coding

关于 Ptges

功能概要

Enables prostaglandin-D synthase activity. Involved in prostaglandin biosynthetic process; regulation of fever generation; and sensory perception of pain. Acts upstream of or within negative regulation of cell population proliferation; positive regulation of prostaglandin secretion; and prostaglandin metabolic process. Located in cytoplasm and nuclear envelope lumen. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human PTGES (prostaglandin E synthase). [provided by Alliance of Genome Resources, Apr 2022]

Ptges 基因产物(1)

mRNA Protein Name
NM_022415.3 NP_071860.1 prostaglandin E synthase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables prostaglandin-D synthase activity IDA
IDA: 通过直接分析推断
11795891 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of cell population proliferation IGI
IGI: 通过遗传相互作用推断
18485889 MGI
acts upstream of or within negative regulation of cell population proliferation IGI
IGI: 通过遗传相互作用推断
18485889 MGI
acts upstream of or within positive regulation of prostaglandin secretion IMP
IMP: 通过突变表型推断
26828067 MGI
involved in prostaglandin biosynthetic process IDA
IDA: 通过直接分析推断
11795891 MGI
acts upstream of or within prostaglandin metabolic process IDA
IDA: 通过直接分析推断
10869354 MGI
involved in regulation of fever generation IMP
IMP: 通过突变表型推断
14566340 MGI
involved in regulation of inflammatory response IMP
IMP: 通过突变表型推断
12835414 MGI
involved in sensory perception of pain IMP
IMP: 通过突变表型推断
12835414 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
12021206 MGI
located in nuclear envelope lumen IDA
IDA: 通过直接分析推断
10869354 MGI
NOT located in nucleus IDA
IDA: 通过直接分析推断
12021206 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

prostaglandin E synthase

glutathione peroxidase PTGES

glutathione transferase PTGES

microsomal prostaglandin E synthase 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptges NCBI NCBI:9536