1. Gene
  2. LIPK - lipase family member K Gene

LIPK - lipase family member K Gene

中文名称:脂肪酶家族成员 K

种属: Homo sapiens

同用名: LIPL2; bA186O14.2

基因 ID: 643414 | 基因类型: protein coding

关于 LIPK

Cytogenetic location: 10q23.31 Genomic coordinates (GRCh38): 10:88,706,249-88,752,776 (from NCBI)

This gene has 1 transcript (splice variant), 153 orthologues and 5 paralogues. Restricted expression toward skin (RPKM 5.3).

功能概要

预测能使脂蛋白脂肪酶活性。预计参与角质化。预测位于细胞外区域。预计在细胞内膜结合的细胞器中具有活性。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable lipoprotein Lipase activity. Predicted to be involved in cornification. Predicted to be located in extracellular region. Predicted to be active in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

LIPK 基因产物(2)

mRNA Protein Name
NM_001080518.2 NP_001073987.1 lipase member K isoform 1 precursor
NM_001378091.1 NP_001365020.1 lipase member K isoform 2 precursor

LIPK 蛋白结构

Abhydro_lipase

Abhydro_lipase: Partial alpha/beta-hydrolase lipase region (35 - 96)

Abhydrolase_1

Abhydrolase_1: alpha/beta hydrolase fold (111 - 384)

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  • 399 a.a.
蛋白主名 其他名称

lipase member K

lipase K

关联疾病

疾病名称 别名
Supratentorial Meningioma
Lipid Pneumonia

Exogenous Lipoid Pneumonia

Lipoid Pneumonitis

Pneumonia, Lipid

Pneumonia Lipid

Lipoid Pneumonia

Lysosomal Acid Lipase Deficiency

Wolman Disease

Cholesteryl Ester Storage Disease

Lal Deficiency

Lipa Deficiency

Cholesterol Ester Storage Disease

CESD

Cholesterol Ester Hydrolase Deficiency

Acid Lipase Deficiency

Acid Esterase Deficiency

Familial Xanthomatosis

Wolman Xanthomatosis

Wolman'S Disease

Wolman'S Or Triglyceride Storage Type Iii Disease

Xanthomatosis, Familial

Liposomal Acid Lipase Deficiency, Wolman Type

Familial Visceral Xanthomatosis

Primary Familial Xanthomatosis

Primary Familial Xanthomatosis With Adrenal Calcification

Acid Lipase Disease

WOD

Acid Cholesteryl Ester Hydrolase Deficiency, Type 2

Lysosomal And Lipase Deficiency
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus LIPK MGD MGI:2679259
Felis catus LIPK VGNC VGNC:63242
Bos taurus LIPK VGNC VGNC:30907
Canis familiaris LIPK VGNC VGNC:52938
Rattus norvegicus LIPK RGD RGD:1309724
Macaca mulatta LIPK VGNC VGNC:74341