1. Gene
  2. Sp5 - trans-acting transcription factor 5 Gene

Sp5 - trans-acting transcription factor 5 Gene

种属: Mus musculus

基因 ID: 64406 | 基因类型: protein coding

关于 Sp5

功能概要

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within bone morphogenesis; cellular response to organic cyclic compound; and post-anal tail morphogenesis. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; brain; branchial arch; embryo ectoderm; and embryo mesenchyme. Orthologous to human SP5 (Sp5 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Sp5 基因产物(1)

mRNA Protein Name
NM_022435.2 NP_071880.1 transcription factor Sp5
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
17090534 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
11071760 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
11071760 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within bone morphogenesis IGI
IGI: 通过遗传相互作用推断
11071760 MGI
acts upstream of or within cellular response to organic cyclic compound IDA
IDA: 通过直接分析推断
25535395 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
17090534 MGI
acts upstream of or within post-anal tail morphogenesis IGI
IGI: 通过遗传相互作用推断
11071760 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

transcription factor Sp5

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sp5 NCBI NCBI:389058
Rattus norvegicus Sp5 NCBI NCBI:296510