1. Gene
  2. Adcy5 - adenylate cyclase 5 Gene

Adcy5 - adenylate cyclase 5 Gene

种属: Rattus norvegicus

基因 ID: 64532 | 基因类型: protein coding

关于 Adcy5

功能概要

Enables calcium- and calmodulin-responsive Adenylate Cyclase activity. Involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; cAMP biosynthetic process; and response to morphine. Located in endosome; membrane raft; and plasma membrane. Colocalizes with sarcolemma. Biomarker of hypertension and type 2 diabetes mellitus. Orthologous to human ADCY5 (Adenylate Cyclase 5). [provided by Alliance of Genome Resources, Apr 2022]

Adcy5 基因产物(1)

mRNA Protein Name
NM_022600.2 NP_072122.2 adenylate cyclase type 5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables adenylate cyclase activity IDA
IDA: 通过直接分析推断
1409703 RGD
enables calcium- and calmodulin-responsive adenylate cyclase activity IDA
IDA: 通过直接分析推断
10894801 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
19549762 RGD
involved in cAMP biosynthetic process IDA
IDA: 通过直接分析推断
10894801 RGD
involved in heart development IEP
IEP: 通过表达模式推断
19734365 RGD
NOT involved in negative regulation of neuron projection development IMP
IMP: 通过突变表型推断
21986494 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endosome IDA
IDA: 通过直接分析推断
17010343 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
15961389 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

adenylate cyclase type 5

ATP pyrophosphate-lyase 5

adenylate cyclase type V

adenylyl cyclase 5

adenylyl cyclase type V

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adcy5 NCBI NCBI:111