2. Gene
  3. Adnp - activity-dependent neuroprotector homeobox Gene

Adnp - activity-dependent neuroprotector homeobox Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 64622 | 基因类型: protein coding

关于 Adnp

功能概要

This gene encodes a member of a protein family characterized by nine zinc finger motifs followed by a homeobox domain. In vitro studies demonstrate that the encoded protein interacts with the brahma-related gene1-associated or hBRM factors (BAF) gene expression regulating complex, components of the protein translation machinery, and microtubule-associated proteins. This gene has been implicated in neuroprotection through various processes that include chromatin remodeling, splicing, cytoskeletal reorganization, and Autophagy. Homozygous mutant knockout mice display embryonic lethality with defects in neural tube closure. [provided by RefSeq, Nov 2016]

Adnp 基因产物(1)

mRNA Protein Name
NM_001347532.2 NP_001334461.1 activity-dependent neuroprotector homeobox protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-tubulin binding IPI
IPI: 通过物理相互作用推断
16893427 RGD
enables copper ion binding IDA
IDA: 通过直接分析推断
14706557 RGD
enables peptide binding IDA
IDA: 通过直接分析推断
14706557 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in activation of protein kinase activity IDA
IDA: 通过直接分析推断
19047645 RGD
involved in cGMP-mediated signaling IDA
IDA: 通过直接分析推断
11438390 RGD
involved in estrous cycle IEP
IEP: 通过表达模式推断
16023261 RGD
involved in intracellular nitric oxide homeostasis IDA
IDA: 通过直接分析推断
16938277 RGD
involved in negative regulation of gene expression IDA
IDA: 通过直接分析推断
15314252 RGD
involved in negative regulation of neuron apoptotic process IDA
IDA: 通过直接分析推断
16938277 RGD
involved in negative regulation of synaptic transmission IMP
IMP: 通过突变表型推断
15963648 RGD
involved in positive regulation of axon extension IDA
IDA: 通过直接分析推断
19047645 RGD
involved in positive regulation of neuron projection development IDA
IDA: 通过直接分析推断
15800376 RGD
involved in positive regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
19047645 RGD
involved in positive regulation of synapse assembly IDA
IDA: 通过直接分析推断
15800376 RGD
involved in response to carbohydrate IEP
IEP: 通过表达模式推断
19130308 RGD
involved in short-term memory IDA
IDA: 通过直接分析推断
12212775 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
18072088 RGD
located in dendrite IDA
IDA: 通过直接分析推断
19130308 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
16845437 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
19130308 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

activity-dependent neuroprotector homeobox protein

NAP peptide

activity-dependent neuroprotective protein

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-105066 Davunetide 99.64% Phase 3
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00389 ADNP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18122 Adnp Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24596 Adnp Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adnp NCBI NCBI:23394
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