2. Gene
  3. Fgf23 - fibroblast growth factor 23 Gene

Fgf23 - fibroblast growth factor 23 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fgf8b

基因 ID: 64654 | 基因类型: protein coding

关于 Fgf23

功能概要

This gene encodes a member of the Fibroblast Growth Factor family. The encoded protein regulates phosphate homeostasis and vitamin D metabolism. Mutation of the related gene in humans causes autosomal dominant hypophosphatemic rickets (ADHR). The secreted protein is further cleaved into N- and C-terminal chains, which results in loss of function. [provided by RefSeq, Mar 2013]

Fgf23 基因产物(2)

mRNA Protein Name
NM_022657.5 NP_073148.1 fibroblast growth factor 23 precursor
NM_022657.5 NP_073148.1 fibroblast growth factor 23 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fibroblast growth factor receptor binding IPI
IPI: 通过物理相互作用推断
16436388 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17086194 MGI
enables type 1 fibroblast growth factor receptor binding IPI
IPI: 通过物理相互作用推断
17086194 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
23523568 MGI
acts upstream of or within MAPK cascade IDA
IDA: 通过直接分析推断
24259513 MGI
involved in calcium ion homeostasis IDA
IDA: 通过直接分析推断
23523568 MGI
acts upstream of or within fibroblast growth factor receptor signaling pathway IPI
IPI: 通过物理相互作用推断
16436388 MGI
acts upstream of or within intracellular phosphate ion homeostasis IMP
IMP: 通过突变表型推断
15579309 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
17086194 MGI
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
17086194 MGI
acts upstream of or within positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
16436388 MGI
acts upstream of or within regulation of bone mineralization IMP
IMP: 通过突变表型推断
15579309 MGI
involved in response to sodium phosphate IDA
IDA: 通过直接分析推断
23523568 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
24259513 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

fibroblast growth factor 23

FGF-23

fibroblast growth factor 8b

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-N1428C Ferric citrate Activator ≥98.0% 否
Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-125961 T3Inh-1 Inhibitor 98.82% 否
HY-150687 ZINC12409120 Inhibitor / 否
HY-RS04900 FGF23 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16734 Fgf23 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23171 Fgf23 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fgf23 NCBI NCBI:8074
Rattus norvegicus Fgf23 NCBI NCBI:170583
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