2. Gene
  3. Srd5a2 - steroid 5 alpha-reductase 2 Gene

Srd5a2 - steroid 5 alpha-reductase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: S5AR 2

基因 ID: 64677 | 基因类型: protein coding

关于 Srd5a2

功能概要

Enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity and amide binding activity. Involved in several processes, including androgen biosynthetic process; animal organ development; and phthalate metabolic process. Located in cell body fiber; cytoplasm; and neuronal cell body. Biomarker of diabetes mellitus and hyperprolactinemia. Human ortholog(s) of this gene implicated in hypospadias and prostate Cancer. Orthologous to human SRD5A2 (steroid 5 alpha-reductase 2). [provided by Alliance of Genome Resources, Apr 2022]

Srd5a2 基因产物(1)

mRNA Protein Name
NM_022711.5 NP_073202.1 3-oxo-5-alpha-steroid 4-dehydrogenase 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity IDA
IDA: 通过直接分析推断
1527072 RGD
enables amide binding IPI
IPI: 通过物理相互作用推断
9328210 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in androgen biosynthetic process IDA
IDA: 通过直接分析推断
12606426 RGD
involved in androgen metabolic process IDA
IDA: 通过直接分析推断
20954080 RGD
involved in biphenyl metabolic process IEP
IEP: 通过表达模式推断
16938428 RGD
involved in bone development IEP
IEP: 通过表达模式推断
15012600 RGD
involved in dibenzo-p-dioxin metabolic process IEP
IEP: 通过表达模式推断
11222880 RGD
involved in female genitalia development IEP
IEP: 通过表达模式推断
9142501 RGD
involved in hippocampus development IEP
IEP: 通过表达模式推断
21047951 RGD
involved in hypothalamus development IEP
IEP: 通过表达模式推断
15804399 RGD
involved in male genitalia development IEP
IEP: 通过表达模式推断
9142501 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
12606426 RGD
involved in phthalate metabolic process IEP
IEP: 通过表达模式推断
20954080 RGD
involved in response to biphenyl IDA
IDA: 通过直接分析推断
12443045 RGD
involved in response to follicle-stimulating hormone IEP
IEP: 通过表达模式推断
12630924 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
16425201 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
17940878 RGD
involved in response to peptide hormone IDA
IDA: 通过直接分析推断
12630924 RGD
involved in response to steroid hormone IEP
IEP: 通过表达模式推断
16076027 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
16595696 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
18978642 RGD
involved in steroid biosynthetic process IDA
IDA: 通过直接分析推断
1527072 RGD
involved in steroid catabolic process IDA
IDA: 通过直接分析推断
1527072 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell body fiber IDA
IDA: 通过直接分析推断
15305365 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
15305365 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

3-oxo-5-alpha-steroid 4-dehydrogenase 2

5 alpha-SR2

SR type 2

steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13755 SRD5A2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21944 Srd5a2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28461 Srd5a2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Srd5a2 NCBI NCBI:6716
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