2. Gene
  3. Tfrc - transferrin receptor Gene

Tfrc - transferrin receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Trfr

基因 ID: 64678 | 基因类型: protein coding

关于 Tfrc

功能概要

Enables HSP70 protein binding activity; chaperone binding activity; and Transferrin Receptor activity. Involved in several processes, including response to copper ion; response to manganese ion; and response to retinoic acid. Located in several cellular components, including cell surface; extracellular exosome; and recycling endosome membrane. Biomarker of duodenal ulcer; hepatocellular carcinoma; muscular atrophy; non-alcoholic fatty liver disease; and nutrition disease. Human ortholog(s) of this gene implicated in breast carcinoma; immunodeficiency 46; multiple myeloma; and ovarian Cancer. Orthologous to human TFRC (Transferrin Receptor). [provided by Alliance of Genome Resources, Apr 2022]

Tfrc 基因产物(1)

mRNA Protein Name
NM_022712.1 NP_073203.1 transferrin receptor protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Hsp70 protein binding IPI
IPI: 通过物理相互作用推断
11133993 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
26728129 RGD
enables protein-folding chaperone binding IPI
IPI: 通过物理相互作用推断
11133993 RGD
enables transferrin receptor activity IDA
IDA: 通过直接分析推断
12707050 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acute-phase response IEP
IEP: 通过表达模式推断
17417667 RGD
involved in response to copper ion IEP
IEP: 通过表达模式推断
17298691 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
17091493 RGD
involved in response to iron ion IEP
IEP: 通过表达模式推断
17060373 RGD
involved in response to manganese ion IEP
IEP: 通过表达模式推断
17060373 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
18340409 RGD
involved in response to retinoic acid IEP
IEP: 通过表达模式推断
18029484 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
15474526 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
21437659 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
17145503 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
10747907 RGD
is active in postsynaptic recycling endosome membrane IDA
IDA: 通过直接分析推断
17145503 RGD
located in recycling endosome membrane IDA
IDA: 通过直接分析推断
10468577 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transferrin receptor protein 1

TR

tfR

tfR1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14431 TFRC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16743 Tfrc Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-173444 HDAC11-IN-3 / 否
HY-RS23180 Tfrc Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990051 Delpacibart Inhibitor 96.11% 否
HY-P990780 Zeleciment 98.85% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tfrc NCBI NCBI:7037
Macaca fascicularis Tfrc NCBI NCBI:102136007
Mus musculus Tfrc NCBI NCBI:22042
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