2. Gene
  3. CREB3L2 - cAMP responsive element binding protein 3 like 2 Gene

CREB3L2 - cAMP responsive element binding protein 3 like 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：cAMP 反应元件结合蛋白 3 like 2

种属: Homo sapiens

同用名: BBF2H7

基因 ID: 64764 | 基因类型: protein coding

关于 CREB3L2

Cytogenetic location: 7q33 Genomic coordinates (GRCh38): 7:137,874,979-138,002,086 (from NCBI)

This gene has 6 transcripts (splice variants), 219 orthologues, 9 paralogues and is associated with 82 phenotypes. Ubiquitous expression in thyroid (RPKM 36.0), placenta (RPKM 17.4) and 24 other tissues.

功能概要

该基因编码绿洲 bZIP 转录因子家族的成员。这个家族的成员可以二聚化，但只能形成同型二聚体。编码的蛋白质是转录激活因子。在某些肿瘤中可以发现 7 号染色体上的该基因与 16 号染色体上融合在肉瘤中的基因之间的易位。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2011 年 12 月]

This gene encodes a member of the oasis bZIP transcription factor family. Members of this family can dimerize but form homodimers only. The encoded protein is a transcriptional activator. Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

CREB3L2 基因产物(3)

mRNA Protein Name
NM_001253775.2 NP_001240704.1 cyclic AMP-responsive element-binding protein 3-like protein 2 isoform 2
NM_001318246.2 NP_001305175.1 cyclic AMP-responsive element-binding protein 3-like protein 2 isoform 3
NM_194071.4 NP_919047.2 cyclic AMP-responsive element-binding protein 3-like protein 2 isoform 1

CREB3L2 蛋白结构

bZIP_1

bZIP_1: bZIP transcription factor (292 - 354)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 520 a.a.
蛋白主名 其他名称

cyclic AMP-responsive element-binding protein 3-like protein 2

B-ZIB transcription factor

关联疾病

疾病名称 别名
Myxofibrosarcoma

Fibromyxosarcoma

Fibromyxoid Sarcoma

Myxoid Malignant Fibrous Histiocytoma

Dermatofibrosarcoma Protuberans, Myxoid
Sarcoma

Connective And Soft Tissue Neoplasm

Tumor Of Soft Tissue And Skeleton

Sarcomas

Sarcoma - Category
Adult Fibrosarcoma
Spindle Cell Liposarcoma
Kidney Fibrosarcoma

Fibrosarcoma Of The Kidney
Isolated Growth Hormone Deficiency, Type Ii

Ighd Ii

Isolated Growth Hormone Deficiency Type Ii

IGHD2

Growth Hormone Deficiency, Isolated, Type Ii

Congenital Ighd Type Ii

Congenital Isolated Gh Deficiency Type Ii

Congenital Isolated Growth Hormone Deficiency Type Ii

Pituitary Dwarfism Due To Isolated Growth Hormone Deficiency Autosomal Dominant

Growth Hormone Deficiency, Isolated, Autosomal Dominant

Pituitary Dwarfism Due To Isolated Growth Hormone Deficiency, Autosomal Dominant

Autosomal Dominant Isolated Growth Hormone Deficiency

Autosomal Dominant Pituitary Dwarfism Due To Isolated Growth Hormone Deficiency

Isolated Growth Hormone Deficiency Type 2

Growth Hormone Deficiency, Isolated Autosomal Dominant

Growth Hormone Deficiency, Isolated, 2

Growth Hormone Deficiency Isolated Autosomal Dominant
Perineurioma

Soft Tissue Perineurioma
Pseudosarcomatous Fibromatosis

Nodular Fasciitis

Pseudosarcomatous Fasciitis

Fasciitis - Nodular

Fasciitis Nodular
Fibrosarcoma

Neoplasms, Fibrous Tissue

Fibrocytic Tumor

Fibrosarcoma Of Soft Tissue

Fibrous Tissue Neoplasm
Ossifying Fibromyxoid Tumor

Ossifying Fibromyxoid Tumour

Ossifying Fibromyxoma
Myxoid Liposarcoma

Myxoid/Round Cell Liposarcoma

Liposarcoma, Myxoid

Mrcls

Myxoliposarcoma

MXLIPO

Liposarcoma Myxoid

Liposarcoma
Chondrosarcoma, Extraskeletal Myxoid

Extraskeletal Myxoid Chondrosarcoma

Emc

Myxoid Extraosseous Chondrosarcoma
Keratosis Follicularis Spinulosa Decalvans

Kfsd

Keratosis Follicularis Spinulosa Decalvans Cum Ophiasi

Keratosis Follicularis Spinulosa Decalvans, X-Linked

Keratosis Follicularis Spinulosa Decalvans, Autosomal Dominant
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03151 CREB3L2 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta CREB3L2 VGNC VGNC:71497
Felis catus CREB3L2 VGNC VGNC:61167
Rattus norvegicus CREB3L2 RGD RGD:1306040
Bos taurus CREB3L2 VGNC VGNC:27695
Mus musculus CREB3L2 MGD MGI:2442695
Canis familiaris CREB3L2 VGNC VGNC:39598
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