2. Gene
  3. ST6GAL1 - ST6 beta-galactoside alpha-2,6-sialyltransferase 1 Gene

ST6GAL1 - ST6 beta-galactoside alpha-2,6-sialyltransferase 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：ST6 β-半乳糖苷 α-2,6-唾液酸转移酶 1

种属: Homo sapiens

同用名: ST6N; CDw75; SIAT1; ST6GalI

基因 ID: 6480 | 基因类型: protein coding

关于 ST6GAL1

Cytogenetic location: 3q27.3 Genomic coordinates (GRCh38): 3:186,930,526-187,078,553 (from NCBI)

This gene has 24 transcripts (splice variants), 232 orthologues and 14 paralogues. Broad expression in liver (RPKM 87.7), lymph node (RPKM 37.8) and 18 other tissues.

功能概要

该基因编码糖基转移酶家族 29 的一个成员。编码的蛋白质是一种 II 型膜蛋白，可催化唾液酸从 CMP-唾液酸转移到含半乳糖的底物。这种蛋白质通常存在于高尔基体中，但可以通过蛋白水解加工成可溶性形式，参与细胞表面碳水化合物决定簇和分化抗原 HB-6、CD75 和 CD76 的生成。该基因被错误地称为 CD75。可变剪接导致多个转录本变体。[RefSeq 提供，2017 年 7 月]

This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]

ST6GAL1 基因产物(4)

mRNA Protein Name
NM_001353916.2 NP_001340845.1 beta-galactoside alpha-2,6-sialyltransferase 1 isoform a
NM_003032.3 NP_003023.1 beta-galactoside alpha-2,6-sialyltransferase 1 isoform a
NM_173216.2 NP_775323.1 beta-galactoside alpha-2,6-sialyltransferase 1 isoform a
NM_173217.2 NP_775324.1 beta-galactoside alpha-2,6-sialyltransferase 1 isoform b

ST6GAL1 蛋白结构

Glyco_transf_29

Glyco_transf_29: Glycosyltransferase family 29 (sialyltransferase) (156 - 388)

  • 0
  • 100
  • 200
  • 300
  • 406 a.a.
蛋白主名 其他名称

beta-galactoside alpha-2,6-sialyltransferase 1

B-cell antigen CD75

重组 ST6GAL1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71116 ST6GAL1 Protein, Human (HEK293, His) P15907 (K27-C406) ≥95%

关联疾病

疾病名称 别名
Colon Adenocarcinoma

Adenocarcinoma Of Colon

Adenocarcinoma Of The Colon

Colonic Adenocarcinoma
Puerperal Pulmonary Embolism

Obstetric Pulmonary Embolism
Swine Influenza

Influenza Due To Influenza A Virus Subtype H1n1
Congenital Muscular Dystrophy-Dystroglycanopathy Type A11

Congenital Muscular Dystrophy-Dystroglycanopathy With Brain And Eye Anomalies Type A11

Mddga11

Walker-Warburg Syndrome Or Muscle-Eye-Brain Disease B3galnt2-Related

Congenital Muscular Dystrophy-Dystroglycanopathy With Brain And Eye Anomalies, Type A11
Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon
Congenital Disorder Of Glycosylation, Type In

Congenital Disorder Of Glycosylation

CDG1N

Congenital Disorders Of Glycosylation

Cdg In

Cdgin

Congenital Disorder Of Glycosylation 1n

Carbohydrate-Deficient Glycoprotein Syndrome

Cdg

Rft1-Cdg

Cdg-In

Congenital Disorder Of Glycosylation Type In

Carbohydrate Deficient Glycoprotein Syndrome

Cdg Syndrome

Congenital Disorder Of Glycosylation In

Carbohydrate-Deficient Glycoprotein Syndromes

Cdg Syndrome Type In

Carbohydrate Deficient Glycoprotein Syndrome Type In

Congenital Disorder Of Glycosylation Type 1n

Man5glcnac2-Pp-Dol Flippase Deficiency

Glycosylation, Congenital Disorder Of

Glycosylation, Congenital Disorder Of, Type In
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13852 ST6GAL1 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus ST6GAL1 MGD MGI:108470
Canis familiaris ST6GAL1 VGNC VGNC:46856
Felis catus ST6GAL1 VGNC VGNC:65726
Bos taurus ST6GAL1 VGNC VGNC:35337
Macaca mulatta ST6GAL1 VGNC VGNC:77823
Rattus norvegicus ST6GAL1 RGD RGD:3676
Others ST6GAL1 NCBI
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