2. Gene
  3. Ireb2 - iron responsive element binding protein 2 Gene

Ireb2 - iron responsive element binding protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Irp2

基因 ID: 64831 | 基因类型: protein coding

关于 Ireb2

功能概要

Enables 4 iron, 4 sulfur cluster binding activity; iron-responsive element binding activity; and regulatory region RNA binding activity. Involved in several processes, including cellular response to decreased oxygen levels; cellular response to epidermal growth factor stimulus; and response to iron ion. Located in axon; cytosol; and neuronal cell body. Used to study anemia. Biomarker of anemia; hyperinsulinism; and iron deficiency anemia. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human IREB2 (iron responsive element binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Ireb2 基因产物(1)

mRNA Protein Name
NM_022863.2 NP_074054.2 iron-responsive element-binding protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 4 iron, 4 sulfur cluster binding IDA
IDA: 通过直接分析推断
7665579 RGD
enables RNA binding IDA
IDA: 通过直接分析推断
21753061 RGD
enables iron-responsive element binding IDA
IDA: 通过直接分析推断
7665579 RGD
enables regulatory region RNA binding IPI
IPI: 通过物理相互作用推断
7523370 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to epidermal growth factor stimulus IDA
IDA: 通过直接分析推断
10889193 RGD
involved in cellular response to hypoxia IDA
IDA: 通过直接分析推断
16135072 RGD
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
22159112 RGD
involved in cellular response to iron(III) ion IDA
IDA: 通过直接分析推断
16135072 RGD
involved in cellular response to iron(III) ion IEP
IEP: 通过表达模式推断
17469137 RGD
involved in cellular response to manganese ion IDA
IDA: 通过直接分析推断
16568477 RGD
involved in cellular response to manganese ion IEP
IEP: 通过表达模式推断
17469137 RGD
involved in cellular response to mercaptoethanol IDA
IDA: 通过直接分析推断
16135072 RGD
involved in cellular response to retinoic acid IEP
IEP: 通过表达模式推断
22154532 RGD
involved in negative regulation of translation IDA
IDA: 通过直接分析推断
7523370 RGD
involved in response to activity IEP
IEP: 通过表达模式推断
24184442 RGD
involved in response to copper ion IEP
IEP: 通过表达模式推断
24024382 RGD
involved in response to hypobaric hypoxia IEP
IEP: 通过表达模式推断
27925282 RGD
involved in response to iron(II) ion IEP
IEP: 通过表达模式推断
19943190 RGD
involved in response to iron(III) ion IDA
IDA: 通过直接分析推断
21753061 RGD
involved in response to kainic acid IEP
IEP: 通过表达模式推断
16328268 RGD
involved in response to retinoic acid IEP
IEP: 通过表达模式推断
19877527 RGD
involved in response to zinc ion IEP
IEP: 通过表达模式推断
24024381 RGD
involved in skeletal muscle atrophy IEP
IEP: 通过表达模式推断
23994517 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
12111837 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
12111837 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

iron-responsive element-binding protein 2

IRE-BP 2

iron regulatory protein 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06901 IREB2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20966 Ireb2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27483 Ireb2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ireb2 NCBI NCBI:3658
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