2. Gene
  3. Pdgfd - platelet derived growth factor D Gene

Pdgfd - platelet derived growth factor D Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Scdgfb; rSCDGF-B

基因 ID: 66018 | 基因类型: protein coding

关于 Pdgfd

功能概要

Predicted to enable platelet-derived growth factor receptor binding activity. Involved in several processes, including cellular response to growth factor stimulus; positive regulation of cell migration; and positive regulation of cell population proliferation. Located in extracellular space. Used to study glomerulonephritis and mesangial proliferative glomerulonephritis. Biomarker of liver cirrhosis; mesangial proliferative glomerulonephritis; and myocardial infarction. Human ortholog(s) of this gene implicated in prostatic hypertrophy. Orthologous to human PDGFD (platelet derived growth Factor D). [provided by Alliance of Genome Resources, Apr 2022]

Pdgfd 基因产物(1)

mRNA Protein Name
NM_023962.3 NP_076452.1 platelet-derived growth factor D precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hydrogen peroxide IEP
IEP: 通过表达模式推断
16189269 RGD
involved in cellular response to platelet-derived growth factor stimulus IEP
IEP: 通过表达模式推断
16039137 RGD
involved in cellular response to transforming growth factor beta stimulus IMP
IMP: 通过突变表型推断
23585135 RGD
involved in positive regulation of fibroblast proliferation IDA
IDA: 通过直接分析推断
21866094 RGD
involved in positive regulation of glomerular mesangial cell proliferation IMP
IMP: 通过突变表型推断
12937299 RGD
involved in positive regulation of monocyte extravasation IMP
IMP: 通过突变表型推断
12937299 RGD
involved in positive regulation of smooth muscle cell chemotaxis IMP
IMP: 通过突变表型推断
15752751 RGD
involved in positive regulation of smooth muscle cell proliferation IDA
IDA: 通过直接分析推断
15752751 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
17397961 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

platelet-derived growth factor D

iris-expressed growth factor

platelet-derived growth factor, D polypeptide

spinal cord-derived growth factor B

spinal-cord derived growth factor-B protein

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10253 PDGFD Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18294 Pdgfd Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24772 Pdgfd Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pdgfd NCBI NCBI:80310
Mus musculus Pdgfd NCBI NCBI:71785
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