2. Gene
  3. Smurf2 - SMAD specific E3 ubiquitin protein ligase 2 Gene

Smurf2 - SMAD specific E3 ubiquitin protein ligase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 2810411E22Rik

基因 ID: 66313 | 基因类型: protein coding

关于 Smurf2

功能概要

Predicted to enable SMAD binding activity; identical protein binding activity; and ubiquitin protein Ligase activity. Predicted to be involved in several processes, including negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; positive regulation of trophoblast cell migration; and ubiquitin-dependent protein catabolic process. Predicted to be located in nuclear speck. Predicted to be part of ubiquitin Ligase complex. Predicted to be active in cytoplasm. Is expressed in cardiovascular system; eye; genitourinary system; gut; and lung. Used to study diffuse large B-cell lymphoma. Orthologous to human SMURF2 (SMAD specific E3 ubiquitin protein Ligase 2). [provided by Alliance of Genome Resources, Apr 2022]

Smurf2 基因产物(2)

mRNA Protein Name
NM_001362894.1 NP_001349823.1 E3 ubiquitin-protein ligase SMURF2 isoform 2
NM_025481.3 NP_079757.2 E3 ubiquitin-protein ligase SMURF2 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19379695 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase SMURF2

HECT-type E3 ubiquitin transferase SMURF2

SMAD ubiquitination regulatory factor 2

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-110204 Heclin Inhibitor 98.21% 否
HY-RS13460 SMURF2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20599 Smurf2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27107 Smurf2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Smurf2 NCBI NCBI:64750
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