2. Gene
  3. Iscu - iron-sulfur cluster assembly enzyme Gene

Iscu - iron-sulfur cluster assembly enzyme Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Nifu; ISCU2; Nifun; 2310020H20Rik

基因 ID: 66383 | 基因类型: protein coding

关于 Iscu

功能概要

Predicted to enable 2 iron, 2 sulfur cluster binding activity; ferrous iron binding activity; and molecular adaptor activity. Predicted to be involved in several processes, including negative regulation of iron ion import across plasma membrane; positive regulation of aconitate hydratase activity; and positive regulation of mitochondrial electron transport, NADH to ubiquinone. Located in mitochondrion. Orthologous to human ISCU (iron-sulfur cluster assembly enzyme). [provided by Alliance of Genome Resources, Apr 2022]

Iscu 基因产物(2)

mRNA Protein Name
NM_001363317.1 NP_001350246.1 iron-sulfur cluster assembly enzyme ISCU, mitochondrial isoform 2
NM_025526.5 NP_079802.1 iron-sulfur cluster assembly enzyme ISCU, mitochondrial isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
29097656 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in [4Fe-4S] cluster assembly IDA
IDA: 通过直接分析推断
25597503 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of mitochondrial [2Fe-2S] assembly complex IDA
IDA: 通过直接分析推断
21298097 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
17597094 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

iron-sulfur cluster assembly enzyme ISCU, mitochondrial

IscU iron-sulfur cluster scaffold homolog

nifU-like N-terminal domain-containing protein

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-145413 BRD2889 Inhibitor / 否
HY-RS06928 ISCU Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18618 Iscu Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25104 Iscu Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Iscu NCBI NCBI:23479
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