2. Gene
  3. Nmnat1 - nicotinamide nucleotide adenylyltransferase 1 Gene

Nmnat1 - nicotinamide nucleotide adenylyltransferase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: nmnat; D4Cole1e; 2610529L11Rik; 5730441G13Rik

基因 ID: 66454 | 基因类型: protein coding

关于 Nmnat1

功能概要

Enables nicotinamide-nucleotide adenylyltransferase activity and nicotinate-nucleotide adenylyltransferase activity. Involved in negative regulation of neuron death. Acts upstream of or within NAD biosynthetic process and response to wounding. Located in nucleus. Used to study Leber congenital amaurosis 9 and retinal degeneration. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 9 and spondyloepiphyseal dysplasia, sensorineural hearing loss, intellectual developmental disorder, and Leber congenital amaurosis. Orthologous to human NMNAT1 (nicotinamide nucleotide adenylyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Nmnat1 基因产物(2)

mRNA Protein Name
NM_001356357.1 NP_001343286.1 nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
NM_133435.2 NP_597679.1 nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables nicotinamide-nucleotide adenylyltransferase activity IDA
IDA: 通过直接分析推断
16914673 MGI
enables nicotinate-nucleotide adenylyltransferase activity IDA
IDA: 通过直接分析推断
15381699 MGI
enables protein ADP-ribosyltransferase-substrate adaptor activity IDA
IDA: 通过直接分析推断
32822587 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within NAD biosynthetic process IDA
IDA: 通过直接分析推断
15381699 MGI
involved in NAD biosynthetic process IMP
IMP: 通过突变表型推断
27735788 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
32822587 MGI
acts upstream of or within response to wounding IDA
IDA: 通过直接分析推断
16914673 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in chromatin IDA
IDA: 通过直接分析推断
32822587 MGI
located in chromatin IDA
IDA: 通过直接分析推断
32822587 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15381699 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

NMN adenylyltransferase 1

NMN/NaMN adenylyltransferase 1

naMN adenylyltransferase 1

nicotinamide mononucleotide adenylyl transferase

nicotinamide mononucleotide adenylyltransferase 1

nicotinamide/nicotinate mononucleotide adenylyltransferase 1

nicot

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-W615108B β-Nicotinamide mononucleotide, reduced form disodium 99.55% 否
HY-161875 NAT1-IN-1 Inhibitor 99.77% 否
HY-161712 IMPDH-IN-4 Inhibitor 99.76% 否
HY-RS09382 NMNAT1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18008 Nmnat1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24481 Nmnat1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nmnat1 NCBI NCBI:64802
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