1. Gene
  2. Aspn - asporin Gene

Aspn - asporin Gene

种属: Mus musculus

同用名: Plap1; Slrr1c; 4631401G09Rik

基因 ID: 66695 | 基因类型: protein coding

关于 Aspn

功能概要

This gene encodes a member of the small leucine-rich proteoglycan family. The encoded protein is an extracellular matrix protein that modulates the transforming growth factor-beta signaling pathway, regulating cartilage matrix gene expression and cartilage formation. The protein plays a role in the pathology of osteoarthritis. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

Aspn 基因产物(2)

mRNA Protein Name
NM_001172481.1 NP_001165952.1 asporin preproprotein
NM_025711.3 NP_079987.2 asporin preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17522060 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of tooth mineralization IDA
IDA: 通过直接分析推断
17522060 MGI
involved in negative regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: 通过直接分析推断
17827158 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular matrix IDA
IDA: 通过直接分析推断
11152692 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

asporin

periodontal ligament-associated protein 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aspn NCBI NCBI:54829