2. Gene
  3. BPHL - biphenyl hydrolase like Gene

BPHL - biphenyl hydrolase like Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：联苯水解酶类

种属: Homo sapiens

同用名: MCNAA; BPH-RP; VACVASE

基因 ID: 670 | 基因类型: protein coding

关于 BPHL

Cytogenetic location: 6p25.2 Genomic coordinates (GRCh38): 6:3,118,376-3,153,578 (from NCBI)

This gene has 12 transcripts (splice variants), 211 orthologues and 12 paralogues. Broad expression in kidney (RPKM 36.5), liver (RPKM 16.0) and 19 other tissues.

功能概要

该基因编码水解酶丝氨酸蛋白酶家族的一个成员，该家族在其活性位点含有一个丝氨酸。编码的蛋白质可能在激活抗病毒药物前体伐昔洛韦中发挥作用。已经描述了选择性剪接的转录变体。[RefSeq 提供，2009 年 1 月]

This gene encodes a member of the serine protease family of hydrolytic enzymes which contain a serine in their active site. The encoded protein may play a role in activation of the Antiviral prodrug valacyclovir. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009]

BPHL 基因产物(2)

mRNA Protein Name
NM_001302777.1 NP_001289706.1 valacyclovir hydrolase isoform 2
NM_004332.4 NP_004323.2 valacyclovir hydrolase isoform 1 precursor

BPHL 蛋白结构

Abhydrolase_6

Abhydrolase_6: Alpha/beta hydrolase family (63 - 284)

  • 0
  • 100
  • 200
  • 291 a.a.
蛋白主名 其他名称

valacyclovir hydrolase

biphenyl hydrolase-like (serine hydrolase)

重组 BPHL 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71838 BPHL Protein, Human (P.pastoris, His-Myc) Q86WA6 (38S-291Q) ≥95%
HY-P76177 BPHL Protein, Human (His) Q86WA6-1 (S38-Q291) ≥95%

关联疾病

疾病名称 别名
Cardiomyopathy, Dilated, 1m

Dilated Cardiomyopathy 1m

CMD1M

Cardiomyopathy, Dilated 1m

Cardiomyopathy, Dilated, Type 1m
Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01579 BPHL Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus BPHL VGNC VGNC:53958
Rattus norvegicus BPHL RGD RGD:1307572
Mus musculus BPHL MGD MGI:1915271
Canis familiaris BPHL VGNC VGNC:38503
Macaca mulatta BPHL VGNC VGNC:70276
Others BPHL NCBI
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