2. Gene
  3. Ndc80 - NDC80 kinetochore complex component Gene

Ndc80 - NDC80 kinetochore complex component Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HEC; HEC1; Kntc2; 2610020P18Rik

基因 ID: 67052 | 基因类型: protein coding

关于 Ndc80

功能概要

Enables cyclin binding activity. Acts upstream of or within kinetochore organization; meiosis I cell cycle process; and regulation of protein stability. Located in centrosome; cytoplasm; and kinetochore. Orthologous to human NDC80 (NDC80 kinetochore complex component). [provided by Alliance of Genome Resources, Apr 2022]

Ndc80 基因产物(1)

mRNA Protein Name
NM_023294.2 NP_075783.2 kinetochore protein NDC80 homolog
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cyclin binding IPI
IPI: 通过物理相互作用推断
23541922 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11591653 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G2/MI transition of meiotic cell cycle IDA
IDA: 通过直接分析推断
23541922 MGI
acts upstream of or within kinetochore organization IMP
IMP: 通过突变表型推断
23541922 MGI
acts upstream of or within mitotic cell cycle checkpoint signaling IMP
IMP: 通过突变表型推断
18940925 MGI
acts upstream of or within regulation of protein stability IMP
IMP: 通过突变表型推断
23541922 MGI
acts upstream of or within skeletal muscle satellite cell proliferation IMP
IMP: 通过突变表型推断
32483152 MGI
acts upstream of or within spindle assembly involved in female meiosis I IGI
IGI: 通过遗传相互作用推断
23541922 MGI
acts upstream of or within spindle assembly involved in female meiosis I IMP
IMP: 通过突变表型推断
23541922 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in centrosome IDA
IDA: 通过直接分析推断
18940925 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
23541922 MGI
located in kinetochore IDA
IDA: 通过直接分析推断
18940925 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

kinetochore protein NDC80 homolog

NDC80 homolog, kinetochore complex component

highly expressed in cancer, rich in leucine heptad repeats

kinetochore associated 2

kinetochore protein Hec1

kinetochore-associated protein 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09105 NDC80 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19722 Ndc80 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26218 Ndc80 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ndc80 NCBI NCBI:10403
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